TELSWIFT 40 (TELMISARTAN TABLETS 40MG)

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

TELMISARTAN

Boleh didapati daripada:

SYNERRV SDN BHD

INN (Nama Antarabangsa):

TELMISARTAN

Unit dalam pakej:

4 x 7 Tablets

Dikeluarkan oleh:

IND-SWIFT LIMITED

Risalah maklumat

TELSWIFT 40/80
TELMISARTAN TABLETS 40MG/80MG
Page 1 of 2
_Consumer Medication Information Leaflet (RiMUP)_
WHAT IS IN THIS LEAFLET?
1.
What Telmisartan Tablets is used
for
2.
How Telmisartan Tablets works
3.
Before you use Telmisartan Tablets
4.
How to use Telmisartan Tablets
5.
While you are using it
6.
Side effects
7.
Storage
and
Disposal
of
Telmisartan Tablets
8.
Product Description
9.
Manufacturer
10.
Product Registration Holder
11.
Date of revision
12.
Serial number
1. WHAT TELMISARTAN TABLETS IS USED
FOR
Telmisartan is used to treat essential
hypertension (high blood pressure) in
adults. ‘Essential’ means that the high
blood pressure is not caused by any
other condition.
Also
used
to
reduce
cardiovascular
events (i.e. heart attack or stroke) in
adults
who
are
at risk
because
they
have a reduced or blocked blood supply
to the heart or legs or have had a stroke
or have high risk diabetes. Your doctor
can tell you if you are at high risk for
such events.
2. HOW TELMISARTAN TABLETS WORKS
Telmisartan
belongs
to
a
class
of
medicines
known
as
angiotensin
II
receptor antagonists. Angiotensin II is a
substance produced in your body which
causes your blood vessels to narrow,
thus
increasing
your
blood
pressure.
Telmisartan
blocks
the
effect
of
angiotensin II so that the blood vessels
relax,
and
your
blood
pressure
is
lowered.
3.
BEFORE
YOU
USE
TELMISARTAN
TABLETS
_-When you must not use it _
Do not take Telmisartan
•
if you are allergic to telmisartan or
any other ingredients of this medicine
•
if
you
are
more
than
3
months
pregnant.
•
if
you
have
severe
liver
problems
such
as
cholestasis
or
biliary
obstruction (problems with drainage of
the bile from the liver and gall bladder)
or any other severe liver disease.
•
if
you
have
diabetes
or
impaired
kidney
function
and
you
are
treated
with
a
blood
pressure
lowering
medicine containing aliskiren.
If any of the above applies to you, tell
your doctor or pharmacist before taking
Telmisartan.
_-Before you start to use it _
Talk
to
your
doctor
before
taking
Telmi

Ciri produk

TELSWIFT 40 (TELMISARTAN TABLETS 40MG)
TELSWIFT 80 (TELMISARTAN TABLETS 80MG)
COMPOSITION
TELSWIFT 40 (TELMISARTAN TABLETS 40 MG)
Each uncoated tablet contains:
Telmisartan BP/Ph.Eur.
40 mg
Excipients q.s.
TELSWIFT 80 (TELMISARTAN TABLETS 80 MG)
Each uncoated tablet contains:
Telmisartan BP/h.Eur.
80 mg
Excipients q.s.
PRESENTATION:
4 Alu Alu blister pack of 7 Tablets
PRODUCT DESCRIPTION :
TELSWIFT 40 (TELMISARTAN TABLETS 40MG) :
White to off white colored, oblong shaped, biconvex,
uncoated tablets with one side breakline and other side plain.
TELSWIFT 80 (TELMISARTAN TABLETS 80MG) :
White to off white colored, oblong shaped, biconvex,
uncoated tablets with both sides plain.
PROPERTIES:
Telmisartan belongs to a group of medicines called angiotensin II
receptor antagonists. It blocks the effect of
angiotensin II so that the blood vessels relax, and your blood
pressure is lowered. Telmisartan is 4’-[[4-Methyl-6-(1-
methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1-yl] methyl]
biphenyl-2-carboxylic acid. The empirical
formula of Telmisartan is C
33
H
30
N
4
O
2
and its molecular weight is 514.6. Its structural formula is
CLINICAL PHARMACOLOGY:
PHARMACODYNAMICS AND MECHANISM OF ACTION:
Pharmacotherapeutic group: Angiotensin II receptor (type AT1)
antagonist, ATC Code : C09CA07
Telmisartan blocks the vasoconstrictor and aldosterone secreting
effects of angiotensin II by selectively blocking the
binding of angiotensin II to the AT1 receptor in many tissues, such as
vascular smooth muscle and the adrenal gland.
Its action is therefore independent of the pathways for angiotensin II
synthesis.
Telmisartan has much greater affinity ( > 3,000 fold) for the AT1
receptor than for the AT2 receptor. Blockade of
the renin-angiotensin system with ACE inhibitors, which inhibit the
biosynthesis of angiotensin II from angiotensin
I, is widely used in the treatment of hypertension. ACE inhibitors
also inhibit the degradation of bradykinin, a
reaction also catalyzed by ACE. Because telmisartan does not inhibit
ACE (kininase II