REXOM WINAMOL 250MG TABLET

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

Paracetamol

Boleh didapati daripada:

KCK PHARMACEUTICAL INDUSTRIES SDN. BHD.

INN (Nama Antarabangsa):

Paracetamol

Unit dalam pakej:

100 Tablets; 30 Tablets; 500 Tablets; 1000 Tablets

Dikeluarkan oleh:

KCK PHARMACEUTICAL INDUSTRIES SDN. BHD.

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
_ _
REXOM
TM
WINAMOL TABLET
Paracetamol (250mg, 500mg, 650mg)
1
WHAT IS IN THIS LEAFLET
1.
What REXOM
TM
Winamol is used
for
2.
How REXOM
TM
Winamol works
3.
Before you use REXOM
TM
Winamol
4.
How to use REXOM
TM
Winamol
5.
While you are using REXOM
TM
Winamol
6.
Side effects
7.
Storage and disposal of REXOM
TM
Winamol
8.
Product description
9.
Manufactured by and Product
Registration Holder
10.
Date of revision
11.
Serial Number
WHAT REXOM
TM WINAMOL IS USED FOR

For the relief of fever

For the relief from mild to moderate
pain
including:
headache,
migraine,
backache, musculoskeletal pain (pain
in bones, muscles, tendons, ligaments
or nerves), muscle pain and sudden
pain due to irritated or damaged nerve,
painful periods, pain of osteoarthritis,
toothache,
pain
after
dental
procedures/tooth extraction, pain after
vaccination and the discomfort from
colds, influenza and sore throats.
HOW REXOM
TM WINAMOL WORKS
Paracetamol
is
a
centrally
acting
analgesic and antipyretic with minimal
anti-inflammatory
properties.
It
works
by
relieving
pain
and
reducing
high
temperature and fever.
BEFORE YOU USE REXOM
TM WINAMOL
_-When you must not use it _
It
should not be used in individuals:
_ _

known
to
be
hypersensitive
to
paracetamol or other components of
the product.

which
have
severe
and
active
liver
impairment.

taken
other
paracetamol
containing
medicines at the same time.
_-Before you start to use it_

Paracetamol should be given with care
to individuals with impaired kidney or
liver function.

Allergy alert: Paracetamol may cause
severe skin reactions. Symptoms may
include skin reddening, blisters or rash.

It should also be given with care to
individuals with alcohol dependence.
_Pregnancy and lactation_
Talk to you doctor before taking this
medicine
if
you
are
pregnant,
might
become pregnant or are breastfeeding.
_ _
_-Taking other medicines _
Inform your doctor or pharmacist before
taking this medicines, including any that
you get without a

Ciri produk

REXOM WINAMOL 250MG TABLET
NAME AND STRENGTH OF ACTIVE SUBSTANCE(S)
Each tablet contains:
Paracetamol
……………………………………….... 250 mg
Preservative:
Potassium Sorbate ……………………………...….. 0.10 %w/w
PRODUCT DESCRIPTION:
White colour, round tablet with top scored
PHARMACODYNAMICS:
Paracetamol is a centrally acting analgesic and antipyretic with
minimal anti-inflammatory
properties.
ANALGESIC:
The mechanism of analgesic action has not been fully determined.
Paracetamol may act
predominantly by inhibiting prostaglandin synthesis in the central
nervous system
(specifically cyclooxygenase (COX)-2) and, to a lesser extent, through
a peripheral action by
blocking pain-impulse generation.
The peripheral action may also be due to inhibition of prostaglandin
synthesis or to inhibition
of the synthesis or actions of other substances that sensitize pain
receptors to mechanical or
chemical stimulation.
ANTIPYRETIC:
Paracetamol act centrally on the hypothalamic heat-regulating center
to produce peripheral
vasodilatation resulting in increase blood flow through the skin,
sweating and heat loss.
Paracetamol reduces fever by inhibiting the formulation and release of
prostaglandins in the
CNS and by inhibiting endogenous pyrogens at the hypothalamic
thermoregulator center.
PHARMACOKINETICS:
Following oral administration paracetamol is rapidly absorbed.
Paracetamol absorption takes place mainly in the small intestine and
therefore the rate of
absorption is depending on the rate of gastric emptying. It has been
shown that drugs which
delay gastric emptying also delay the absorption of paracetamol
whereas metoclopramide (a
drug which increases the rate of gastric emptying) accelerates
absorption of the analgesic
through the total amount absorbed doses not increase.
The presence of food in the stomach has also been reported to reduce
the rate of absorption of
paracetamol. Alterations in gastric pH have no appreciable effect on
paracetamol absorption.
During absorption, the amount of paraceta