Country: Մալայզիա
language: անգլերեն
source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Paracetamol
KCK PHARMACEUTICAL INDUSTRIES SDN. BHD.
Paracetamol
100 Tablets; 30 Tablets; 500 Tablets; 1000 Tablets
KCK PHARMACEUTICAL INDUSTRIES SDN. BHD.
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ _ _ REXOM TM WINAMOL TABLET Paracetamol (250mg, 500mg, 650mg) 1 WHAT IS IN THIS LEAFLET 1. What REXOM TM Winamol is used for 2. How REXOM TM Winamol works 3. Before you use REXOM TM Winamol 4. How to use REXOM TM Winamol 5. While you are using REXOM TM Winamol 6. Side effects 7. Storage and disposal of REXOM TM Winamol 8. Product description 9. Manufactured by and Product Registration Holder 10. Date of revision 11. Serial Number WHAT REXOM TM WINAMOL IS USED FOR For the relief of fever For the relief from mild to moderate pain including: headache, migraine, backache, musculoskeletal pain (pain in bones, muscles, tendons, ligaments or nerves), muscle pain and sudden pain due to irritated or damaged nerve, painful periods, pain of osteoarthritis, toothache, pain after dental procedures/tooth extraction, pain after vaccination and the discomfort from colds, influenza and sore throats. HOW REXOM TM WINAMOL WORKS Paracetamol is a centrally acting analgesic and antipyretic with minimal anti-inflammatory properties. It works by relieving pain and reducing high temperature and fever. BEFORE YOU USE REXOM TM WINAMOL _-When you must not use it _ It should not be used in individuals: _ _ known to be hypersensitive to paracetamol or other components of the product. which have severe and active liver impairment. taken other paracetamol containing medicines at the same time. _-Before you start to use it_ Paracetamol should be given with care to individuals with impaired kidney or liver function. Allergy alert: Paracetamol may cause severe skin reactions. Symptoms may include skin reddening, blisters or rash. It should also be given with care to individuals with alcohol dependence. _Pregnancy and lactation_ Talk to you doctor before taking this medicine if you are pregnant, might become pregnant or are breastfeeding. _ _ _-Taking other medicines _ Inform your doctor or pharmacist before taking this medicines, including any that you get without a read_full_document
REXOM WINAMOL 250MG TABLET NAME AND STRENGTH OF ACTIVE SUBSTANCE(S) Each tablet contains: Paracetamol ……………………………………….... 250 mg Preservative: Potassium Sorbate ……………………………...….. 0.10 %w/w PRODUCT DESCRIPTION: White colour, round tablet with top scored PHARMACODYNAMICS: Paracetamol is a centrally acting analgesic and antipyretic with minimal anti-inflammatory properties. ANALGESIC: The mechanism of analgesic action has not been fully determined. Paracetamol may act predominantly by inhibiting prostaglandin synthesis in the central nervous system (specifically cyclooxygenase (COX)-2) and, to a lesser extent, through a peripheral action by blocking pain-impulse generation. The peripheral action may also be due to inhibition of prostaglandin synthesis or to inhibition of the synthesis or actions of other substances that sensitize pain receptors to mechanical or chemical stimulation. ANTIPYRETIC: Paracetamol act centrally on the hypothalamic heat-regulating center to produce peripheral vasodilatation resulting in increase blood flow through the skin, sweating and heat loss. Paracetamol reduces fever by inhibiting the formulation and release of prostaglandins in the CNS and by inhibiting endogenous pyrogens at the hypothalamic thermoregulator center. PHARMACOKINETICS: Following oral administration paracetamol is rapidly absorbed. Paracetamol absorption takes place mainly in the small intestine and therefore the rate of absorption is depending on the rate of gastric emptying. It has been shown that drugs which delay gastric emptying also delay the absorption of paracetamol whereas metoclopramide (a drug which increases the rate of gastric emptying) accelerates absorption of the analgesic through the total amount absorbed doses not increase. The presence of food in the stomach has also been reported to reduce the rate of absorption of paracetamol. Alterations in gastric pH have no appreciable effect on paracetamol absorption. During absorption, the amount of paraceta read_full_document