GLUMET FORTE 850 MG TABLET

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

METFORMIN HYDROCHLORIDE

Boleh didapati daripada:

PHARMANIAGA MANUFACTURING BERHAD

INN (Nama Antarabangsa):

METFORMIN HYDROCHLORIDE

Unit dalam pakej:

10 Tablets; 20 Tablets; 15 Tablets; 100 Tablets

Dikeluarkan oleh:

PHARMANIAGA MANUFACTURING BERHAD

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
_ _
GLUMET FORTE TABLET
_®_
_ _
Metformin Hydrochloride (850 mg)
1
WHAT IS IN THIS LEAFLET
1.
What Glumet Forte Tablet 850mg
is used for
2.
How Glumet Forte Tablet 850mg
works
3.
Before you use Glumet Forte
Tablet 850mg
4.
How to take Glumet Forte Tablet
850mg
5.
While you are using Glumet Forte
Tablet 850mg
6.
Side effects
7.
Storage and Disposal of Glumet
Forte Tablet 850mg
8.
Product description
9.
Manufacturer and Product
Registration Holder
10.
Date of Revision
WHAT GLUMET FORTE TABLET 850MG
IS USED FOR
Glumet Forte Tablet is used to treat
diabetes
by
regulating
the
level
of
sugar in the blood.
Glumet
Forte
Tablet
is
prolonged-
release medicine. This means that the
release of the medication is spread
over longer period of time than an
immediate-release medicine.
Ask your doctor or pharmacist if you
need additional information.
HOW GLUMET FORTE TABLET 850MG
WORKS
Glumet
Forte
Tablet
works
by
improving the sensitivity of your body
to insulin. It helps your body to use
glucose in the normal way again.
BEFORE YOU USE GLUMET FORTE TABLET
850MG
_When you must not take it _
Do
not
take
Glumet
Forte
Tablet
850mg:
_ _
•
If you are allergic (hypersensitivity)
to metformin or any of the other
ingredients in this medicine.
•
If
you
have
any
type
of
acute
metabolic
acidosis
(serious
electrolyte disorder) such as lactic
acidosis,
diabetic
ketoacidosis.
Lactic acidosis [too much lactic acid
in the blood (see "Risk of lactic
acidosis" below)] or ketoacidosis.
Ketoacidosis is a condition in which
substances
called
'ketone
bodies'
accumulate in the blood and which
can
lead
to
diabetic
pre-coma.
Symptoms of acidosis may include
stomach pain, abnormal breathing
and drowsiness (if severe).
•
If you have severely reduced kidney
function
which
could
lead
to
dehydration, death of kidney tissue
and shock.
•
If you have liver problems.
•
If you are suffering from acute and
severe diseases which causes region
of the body deprived of adequate
oxygen supply (tissue hypoxia).
�

Ciri produk

Ⓡ
GLUMET
-FORTE
METFORMIN HCL 850MG
TABLET 850 MG
_SURGERY_
Metformin must be discontinued at the time of surgery under
general,
spinal
or
epidural
anaesthesia.
Therapy
may
be
restarted no earlier than 48 hours following surgery or resump-
tion of oral nutrition and provided that renal function has been
re-evaluated and found to be stable.
_CARDIAC FUNCTION_
Patients with heart failure are more at risk of hypoxia and renal
insufficiency.
In
patients
with
stable
chronic
heart
failure,
metformin may be used with a regular monitoring of cardiac and
renal function. For patients with acute and unstable heart failure,
metformin is contraindicated.
_HEPATIC IMPAIRMENT_
Patients with hepatic impairment have developed cases of
metformin-associated lactic acidosis. This may due to impaired
lactate
clearance
resulting
in
higher
lactate
blood
levels.
Therefore, avoid use of metformin in patients with clinical or
laboratory evidence of hepatic disease.
_VITAMIN B_
_12_
_ DEFICIENCY_
A decrease to subnormal levels of previously normal serum
vitamin B
12
levels was observed in patients. Such decrease,
possibly
due
to
interference
with
B
12
absorption
from
the
B
12
-intrinsic factor complex, may be associated with anaemia
but appears to be rapidly reversible with discontinuation of
metformin or vitamin B
12
supplementation. Certain individuals
(those
with
inadequate
vitamin
B
12
or
calcium
intake
or
absorption) appear to be predisposed to developing subnormal
vitamin B
12
levels. Measure haematologic parameters on an
annual basis and vitamin B
12
at 2 to 3 year intervals in patients
on metformin and manage any abnormalities.
_PAEDIATRIC POPULATION_
The diagnosis of type 2 diabetes mellitus should be confirmed
before treatment with metformin is initiated.
No effect of metformin on growth and puberty has been detected
but no long-term data on these specific points are available.
Therefore, a careful follow-up of the effect of metformin on these
parameters in metformin-treated children, especially prepubes-
cent children, is reco