Amnoz Tablet 5 mg

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

AMLODIPINE BESYLATE

Boleh didapati daripada:

PHARMANIAGA MANUFACTURING BERHAD

INN (Nama Antarabangsa):

AMLODIPINE BESYLATE

Unit dalam pakej:

10 x 10s Tablets

Dikeluarkan oleh:

PHARMANIAGA MANUFACTURING BERHAD

Risalah maklumat

AMNOZ TABLET
Amlodipine (5mg, 10mg)
1
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
WHAT IS IN THIS LEAFLET
1.
What Amnoz Tablet is used for
2.
How Amnoz Tablet works
3.
Before you use Amnoz Tablet
4.
How to use Amnoz Tablet
5.
While you are using it
6.
Side effects
7.
Storage
and
Disposal
of
Amnoz
Tablet
8.
Product Description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
11.
Serial number
WHAT AMNOZ TABLET IS USED FOR
Amnoz Tablet is used for the first line
treatment
of
high
blood
pressure
(hypertension) and can be used for the
first
line
treatment
of
myocardial
ischemia (decrease of blood flow in the
blood
vessel
which
leads
to
reduced
oxygen supply in the heart) due to a
certain type of chest pain called angina,
whether fixed
obstruction
(stable
angina)
and
/
or
vasospasm
/
vasoconstriction (Prinzmetal’s
or
variant angina).
HOW AMNOZ TABLET WORKS
Amnoz
Tablet
works
by
relaxing
the
blood vessels so that the blood passes
through them more easily and high blood
pressure is reduced. In addition, Amnoz
Tablet can improve blood supply to the
heart muscle and receives more oxygen,
so that the chest pain is prevented.
BEFORE YOU USE AMNOZ TABLET
_-When you must not use it _
Do not take this medicine if you are:
•
Allergic
or
hypersensitive
to
dihydropyridines,
amlodipine
or
any of the excipients.
_ _
_-Before you start to use it _
Tell your doctor if you have or had any
of the following conditions:
•
heart failure
•
impaired liver function
If you are pregnant or intend to become
pregnant, and breast-feeding, consult with
your doctor or pharmacist, the possible
risks and benefits of using Amnoz Tablet
during pregnancy and breast-feeding.
If you have not told your doctor about any
of the above, tell him/her before you start
taking Amnoz Tablet.
_ _
_ _
_-Taking other medicines _
Please tell your doctor or pharmacist if
you are taking other medicines including
medicines
without
prescription
from
a
pharmacy,
medical
hall
or
any
other
source.
Some medicines and beverage might have
intera

Ciri produk

Amlodipine was associated with increased reports of pulmonary edema
despite no
significant difference in the incidence of worsening heart failure
compared to placebo.
Calcium channel blockers, including amlodipine, should be used with
caution in
patients with congestive heart failure, as they may increase the risk
of future
cardiovascular events and mortality.
_USE IN PATIENTS WITH IMPAIRED HEPATIC FUNCTION _
As with all calcium antagonists, amlodipine half-life is prolonged and
AUC values are
higher in patients with impaired liver function and dosage
recommendations have not
been established. The drug should therefore be administered with
caution in these
patients.
Amlodipine should therefore be initiated at the lower end of the
dosing range and
caution should be used, both on initial treatment and when increasing
the dose. Slow
dose titration and careful monitoring may be required in patients with
severe hepatic
impairment.
There are no data to support the use of amlodipine alone, during or
within one month
of a myocardial infarction.
_EFFECTS ON ABILITY TO DRIVE AND USE MACHINES_
Amlodipine can have minor or moderate influence on the ability to
drive and use
machines. If patients taking amlodipine suffer from dizziness,
headache, fatigue or
nausea the ability to react may be impaired. Caution is recommended
especially at
the start of treatment.
INTERACTIONS WITH OTHER MEDICAMENTS
Amlodipine has been safely administered with thiazide diuretics, alpha
blockers, beta
blockers, angiotensin-converting enzyme inhibitors, long-acting
nitrates, sublingual
nitroglycerine,
non-steroidal
anti-inflammatory
drugs,
antibiotics,
and
oral
hypoglycemic drugs. Amlodipine has no effect on protein binding of the
drugs tested
(digoxin, phenytoin, warfarin, or indomethacin).
_ _
_EFFECT OF OTHER AGENTS ON AMLODIPINE_
GRAPEFRUIT JUICE: Administration of amlodipine with grapefruit or
grapefruit juice
is not recommended as bioavailability may be increased in some
patients resulting in
increased blood pressure lowering effects.
SIMVAST