AETOS PARACETAMOL 250MG 5ML SUSPENSION

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

Paracetamol

Boleh didapati daripada:

ABIOTIDE SDN. BHD.

INN (Nama Antarabangsa):

Paracetamol

Unit dalam pakej:

120 ml

Dikeluarkan oleh:

HOVID BERHAD

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
AETOS PARACETAMOL 250MG/5ML
SUSPENSION
Paracetamol (250 mg in 5 ml)
1
WHAT IS IN THIS LEAFLET
1.
What Aetos Paracetamol
Suspension is used for
2.
How Aetos Paracetamol
Suspension works
3.
Before you use Aetos Paracetamol
Suspension
4.
How to use Aetos Paracetamol
Suspension
5.
While you are using Paracetamol
Suspension
6.
Side effects
7.
Storage and Disposal of
Paracetamol Suspension
8.
Product description
9.
Manufacturer and Product
Registration Holder
10.
Date of revision
WHAT AETOS PARACETAMOL SUSPENSION
IS USED FOR
Aetos Paracetamol Suspension is used
to relief fever, headache and symptoms
of colds and flu, toothache, discomfort
of teething and fever after vaccination.
HOW AETOS PARACETAMOL SUSPENSION
WORKS
Aetos Paracetamol Suspension contains
Paracetamol that helps to block pain
stimulation and it acts on heat-
regulating center in brain. This results
in increase in blood flow through skin,
sweating and heat loss.
BEFORE YOU USE AETOS PARACETAMOL
SUSPENSION
_ _
_- When you must not use it _
Do not take this medicine if:
•
You have ever had an allergic
reaction to paracetamol.
•
You have severe and active liver
impairment.
This preparation contains
PARACETAMOL. Do not take any
other paracetamol containing medicines
at the same time.
If you are not sure whether you should
start taking this medicine, talk to your
pharmacist or doctor.
_- Before you start to use it _
Tell your doctor if you are taking or
have recently taken any other
medicines, including medicines
obtained without a prescription, as they
may interact with Aetos Paracetamol
Suspension.
Allergy alert: Paracetamol may cause
severe skin reactions. Symptoms may
include skin reddening, blisters or rash.
These could be signs of a serious
condition. If these reactions occur, stop
use and seek medical assistance right
away.
_ _
_- Taking other medicines_
The use of anti-psychotic medicines
such as barbiturate, tricyclic
antidepressants and alcohol may
increase liver toxicity of the
paracetamol.
Medi

Ciri produk

DESCRIPTION
Pink, viscous suspension with raspberry flavour.
COMPOSITION
Each 5 ml contains:
Paracetamol 250 mg
PHARMACODYNAMICS
Paracetamol
is
a
centrally
acting
analgesic
and
antipyretic
with
minimal anti-inflammatory properties.
ANALGESIC:
The mechanism of analgesic action has not been fully determined.
Paracetamol
may
act
predominantly
by
inhibiting
prostaglandin
synthesis in the central nervous system (specifically cyclooxygenase
(COX)-2) and, to a lesser extent, through a peripheral action by
blocking pain-impulse generation.
The peripheral action may also be due to inhibition of prostaglandin
synthesis
or
to
inhibition
of
the
synthesis
or
actions
of
other
substances that sensitize pain receptors to mechanical or chemical
stimulation.
ANTIPYRETIC:
Paracetamol act centrally on the hypothalamic heat-regulating
center to produce peripheral vasodilatation resulting in increase
blood
flow through the skin, sweating and heat loss. Paracetamol reduces
fever by inhibiting the formulation and release of prostaglandins in
the
CNS and by inhibiting endogenous pyrogens at the hypothalamic
thermoregulator center.
PHARMACOKINETICS
Following oral administration paracetamol is rapidly absorbed.
Paracetamol absorption takes place mainly in the small intestine and
therefore the rate of absorption is depending on the rate of gastric
emptying. It has been shown that drugs which delay gastric emptying
also delay the absorption of paracetamol whereas metoclopramide (a
drug
which
increases
the
rate
of
gastric
emptying)
accelerates
absorption of the analgesic through the total amount absorbed doses
not increase.
The presence of food in the stomach has also been reported to reduce
the rate of absorption of paracetamol. Alterations in gastric pH have
no
appreciable effect on paracetamol absorption. During absorption, the
amount of paracetamol which is inactivated is negligible and it has
been
shown
that
paracetamol
does
not
affect
gastric
mucosal
permeability and does not produce mucosal bleeding.
Peak plasma concentrations are reac