Maduramicin Ammonium Premix 1% Powder

Valsts: Malaizija

Valoda: angļu

Klimata pārmaiņas: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktīvā sastāvdaļa:

MADURAMICIN AMMONIUM

Pieejams no:

Weissen Company (m) Sdn. Bhd.

SNN (starptautisko nepatentēto nosaukumu):

MADURAMICIN AMMONIUM

Vienības iepakojumā:

25.00 mcg/mL

Ražojis:

Zhejiang Apeloa Kangyu Bio-Pharmaceutical Co.,Ltd

Produkta apraksts

PACKAGE
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Maduramicin Ammonium Premix 1%
Brand or product Name
Maduramicin Ammonium Premix 1% Powder
Name and strength of
active substance(s)
Maduramicin ammonium 1%
Product Description
Pale yellow to russet brown powder or granule
Pharmacodynamics
Maduramicin is a monovalent glycoside polyether ionophore
antibiotic. It induces an anticoccidial effect on the asexual forms
(sporozoites, merozoites and falciform bodies) of the endogenous
development of coccidia in poultry, some resistant forms to other
ionophore antibiotics included. Its anticoccidial activity is due to
disorder in ion metabolism (potassium and sodium in particular).
Pharmacokinetics
Maduramicin was excreted rapidly in chickens. Steady state was
observed after three days in the excreta, but after six days in
plasma. Maduramicin was the main compound excreted (26 %).
Odemethylation represented the
main
metabolic
pathway of
maduramicin common to chickens and rats. Liver is the target
tissue; maduramicin is the marker residue in all tissues tested.
Tissue residue kinetics of total residues and marker residue indicate
a rapid decline of residues in all tissues. Ratios maduramicin to
total residues have been established.
Environmental
Properties
Not Applicable
Indication
As an aid in the prevention of coccidiosis caused by Eimeria
necatrix
,
E. tenella
,
E. acervulina
,
E. brunetti
,
E. maxima and E.
mivati
.
Recommended Dosage
Thoroughly mix the product into the feed at a level of 500gm per
tonne of broiler feed to obtain a concentration of 5g/t maduramicin
ammonium in the complete feed. Feed containing the product
should be the only ration fed to broilers to avoid dilution of the
active ingredient.
Mode of
Administration
Oral route, by mixing the product with feeding stuff
Contraindication
None.
Warning and
precaution
For use in feeds intended for chicken only.
Do not mix with or use simultaneously with feed containing
another anticoccidial.
Direct contact with the skin is to be avoided. When mixing and
handling this product, use protective c