Valsts: Dienvidāfrikas Republika
Valoda: angļu
Klimata pārmaiņas: South African Health Products Regulatory Authority (SAHPRA)
Janssen
INDICATIONS [/za_1287.html#1] [/za_1287.html#1] [/za_1287.html#1] CONTRA-INDICATIONS [/za_1287.html#1] [/za_1287.html#1] DOSAGE [/za_1287.html#1] [/za_1287.html#1] SIDE-EFFECTS [/za_1287.html#1] [/za_1287.html#1] [/za_1287.html#1] PREGNANCY [/za_1287.html#1] [/za_1287.html#1] OVERDOSE [/za_1287.html#1] IDENTIFICATION [/za_1287.html#1] [/za_1287.html#1] PATIENT INFORMATION IMODIUM PLUS™ © J-C 2000 SCHEDULING STATUS: Schedule 2 PROPRIETARY NAME (and dosage form): IMODIUM PLUS™ CHEWABLE TABLETS. COMPOSITION Each chewable tablet contains 2 mg LOPERAMIDE hydrochloride and 125 mg SIMETHICONE . PHARMACOLOGICAL CLASSIFICATION A.11.9 2 Medicines acting on gastro-intestinal tract. Other. PHARMACOLOGICAL ACTION Loperamide hydrochloride inhibits hypermotility by direct action on the bowel wall. Its inhibition of peristalsis is the result of decreasing the activity of both the longitudinal muscles (preparatory and reflex phases) and the circular muscles (reflex phase). Loperamide hydrochloride normalises the stool in acute diarrhoea. Loperamide hydrochloride is incompletely absorbed from the gut, and it is almost completely metabolised in the liver where it is conjugated and excreted via the bile. Loperamide hydrochloride is mainly eliminated via the faeces. Simethicone is a nonabsorbable inert surface acting agent with antifoaming properties. INDICATIONS ADULTS AND CHILDREN 12 YEARS AND OLDER IMODIUM Plus is indicated for the control and symptomatic relief of acute and chronic non-specific diarrhoea and its commonly associated symptoms: discomfort, bloating, cramping and flatulence. It also inhibits peristalsis and slow intestinal transit time in patients with ileostomies, colostomies and other intestinal resections. CONTRA-INDICATIONS IMODIUM Plus is Izlasiet visu dokumentu