Valsts: Austrālija
Valoda: angļu
Klimata pārmaiņas: Department of Health (Therapeutic Goods Administration)
Tramadol hydrochloride
Actavis Pty Ltd
Medicine Registered
GA TRAMADOL CAPSULES _Tramadol hydrochloride_ Page 1 of 3 GA Tramadol V2 100528 CONSUMER MEDICINE INFORMATION _ _ WHAT IS IN THIS LEAFLET This leaflet answers some common questions about GA Tramadol. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking GA Tramadol against the benefits this medicine is expected to have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET. You may need to read it again. WHAT GA TRAMADOL IS USED FOR GA Tramadol is used to relieve moderate to severe pain and belongs to a group of medicines called analgesics (pain relievers). Your doctor may have prescribed GA Tramadol for another reason. Ask your doctor why GA Tramadol has been prescribed for you. This medicine is available only with a doctor's prescription. GA Tramadol is not normally addictive although some cases have been reported. BEFORE YOU USE GA TRAMADOL _When you must not use it _ _ _ Do not use GA Tramadol if: • YOU HAVE A KNOWN ALLERGY TO GA TRAMADOL OR ANY OF THE INGREDIENTS LISTED AT THE END OF THIS LEAFLET. Some of the symptoms of an allergic reaction may include skin rash, itching, difficulty breathing and swelling of the face (including lips, tongue, throat etc) • YOU ARE TAKING MEDICINE FOR DEPRESSION CONTAINING A "MONOAMINE OXIDASE INHIBITOR" (SUCH AS NARDIL, PARNATE), OR HAVE TAKEN ONE WITHIN THE PAST TWO WEEKS. DO NOT USE GA TRAMADOL AFTER THE EXPIRY DATE PRINTED ON THE PACK. If you take this medicine after the expiry date has passed, it may not work as well. DO NOT USE GA TRAMADOL IF THE PACKAGING IS TORN OR SHOWS SIGNS OF TAMPERING. DO NOT GIVE GA Izlasiet visu dokumentu
PR RODUCT T INFOR RMATIO ON G GA TRAMA ADOL 50 M MG CAPSULEES NA AME OF T THE MEDICINE The activ e product, G ve ingredien GA Tramado nt. ol 50 mg cap psules, conttains tramad dol hydroch hloride as th he Thee chemical sstructure of tramadol hy ydrochlorid de is: [http://www.pharmacopoeia.co.uk/ixbin/bp.cgi?a=imagezoom&file=bp2008_v2_09_medicinal_and_pharmaceutical_substances_09/large/5_tram1.png] CAS S number: 3 36282-47-0 DESCRIPTIO ON AND COMPOS SITION The [(dim Mol Tram read part The cellu titan CL PHA ami sour Tramadol V2 e chemical n methylamin lecular form madol hydr dily soluble tition coeffi e excipients ulose – mic nium dioxid LINICAL P ARMACODYN inocyclohex rces, nor is 100528 name of tram no)methyl)] mula: C 16 H 2 rochloride is in both wat cient is 1.35 contained i crocrystallin de, quinolin PHARMA NAMICS: Tram xanol group it chemical madol hydro -1-(3-metho ochloride is oxyphenyl) s (1_RS_,2_RS_) cyclohexan -2- nol hydrochlloride. 5 NO 2 .HCl. MW: 299.8 84. s an odourle ter and etha 5 at pH 7. ess, white to anol and has o off white c s a pKa of 9 crystalline p 9.41. The w powder that ater/n-octan t is nol in the produ ne, silica – c e yellow, ir uct include c colloidal anh ron oxide ye croscarmell hydrous, m ellow, Brilli lose sodium agnesium st iant Blue FC m, povidone, tearate, gela CF. , atin, ACOLOGY Y madol is a c with opioid ly related to centrally ac d-like effect o opiates. ting synthet ts. It is not tic analgesi derived fro c of the om natural GA T Page 1 of 11 Although the mode of action is not completely understood, at least two complementary mechanisms appear applicable: binding to _µ_-opioid receptors and inhibition of re-uptake of noradrenaline and serotonin. The opioid like activity of tramadol derives from low affinity binding of the parent compound to _µ_-opioid receptors and higher affinity binding of the princi Izlasiet visu dokumentu