Šalis: Naujoji Zelandija
kalba: anglų
Šaltinis: Medsafe (Medicines Safety Authority)
Hydrochlorothiazide 12.5mg; ; ; Losartan potassium 50mg;
Merck Sharp & Dohme (New Zealand) Limited
Hydrochlorothiazide 12.5 mg
50mg/12.5mg
Film coated tablet
Active: Hydrochlorothiazide 12.5mg Losartan potassium 50mg Excipient: Carnauba wax Hyprolose Hypromellose Lactose monohydrate Magnesium stearate Microcrystalline cellulose Quinoline yellow Starch Titanium dioxide
Calendar pack, 15 foil blister, professional sample pack, 15 tablets
Prescription
Prescription
Plantex Ltd
Hypertension HYZAAR is indicated for the treatment of hypertension, for patients in whom combination therapy is appropriate. Reduction in the Risk of Cardiovascular Morbidity and Mortality in Hypertensive Patients with Left Ventricular Hypertrophy HYZAAR is a combination of losartan (COZAAR) and hydrochlorothiazide. In patients with hypertension and left ventricular hypertrophy, losartan, often in combination with hydrochlorothiazide, reduces the risk of cardiovascular morbidity and mortality as measured by the combined incidence of cardiovascular death, stroke, and myocardial infarction in hypertensive patients with left ventricular hypertrophy.
Package - Contents - Shelf Life: Calendar pack, foil blister, professional sample pack - 15 tablets - 36 months from date of manufacture stored at or below 30°C - Calendar pack, foil blisters - 30 tablets - 36 months from date of manufacture stored at or below 30°C
1994-02-23
1 HYZAAR ® _losartan potassium and hydrochlorothiazide _ 50/12.5 mg tablet WHAT IS IN THIS LEAFLET This leaflet answers some common questions about HYZAAR. It does not contain all the available information. It does not take the place of talking to your doctor and pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking HYZAAR against the benefits they expect it will have for you. If you have any concerns about taking this medicine, ask your doctor or pharmacist. Keep this leaflet with the medicine. You may need to read it again. WHAT HYZAAR IS USED FOR HYZAAR lowers high blood pressure, which doctors call hypertension. It may be used alone or in combination with other medicines. In patients with high blood pressure and a thickening of the left ventricle, losartan, often in combination with hydrochlorothiazide, reduces the risk of stroke and heart attack and helps patients live longer. Everyone has blood pressure. This pressure helps get your blood all around your body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have hypertension (high blood pressure) when your blood pressure stays higher than is needed, even when you are calm and relaxed. There are usually no symptoms of hypertension. The only way of knowing that you have hypertension is to have your blood pressure checked on a regular basis. If high blood pressure is not treated it can lead to serious health problems. You may feel fine and have no symptoms, but eventually hypertension can cause stroke, heart disease or kidney failure. Over time, high blood pressure causes the heart to work harder, which can lead to a thickening of the left ventricle. A thickening of the left ventricle of the heart is associated with an increased chance of experiencing a stroke. Your doctor may have prescribed HYZAAR for another reason. Ask your doctor if you have any questions about why HYZAAR has been prescribed for you. HYZAAR is not addictive. HOW DOES HYZAAR WORK Perskaitykite visą dokumentą
Page 1 of 17 NEW ZEALAND DATA SHEET 1 PRODUCT NAME HYZAAR ® 50/12.5 mg tablet 2 QUALITATIVE AND QUANTITATIVE COMPOSITION losartan potassium 50 mg hydrochlorothiazide 12.5 mg For the full list of excipients, see section 6.1. 3 PHARMACEUTICAL FORM A yellow oval shaped film-coated tablet with 717 on one side and plain on the other. Dimensions 11.21 mm x 6.05 mm. 4 CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS Hypertension HYZAAR is indicated for the treatment of hypertension, for patients in whom combination therapy is appropriate. Reduction in the Risk of Cardiovascular Morbidity and Mortality in Hypertensive Patients with Left Ventricular Hypertrophy HYZAAR is a combination of losartan and hydrochlorothiazide. In patients with hypertension and left ventricular hypertrophy, losartan, often in combination with hydrochlorothiazide, reduces the risk of cardiovascular morbidity and mortality as measured by the combined incidence of cardiovascular death, stroke, and myocardial infarction in hypertensive patients with left ventricular hypertrophy (see Section 4.4, _Race_). 4.2 DOSE AND METHOD OF ADMINISTRATION DOSE Hypertension The usual starting and maintenance dose of HYZAAR is one tablet once daily. For patients who do not respond adequately to HYZAAR, the dosage may be increased to two tablets once daily. The maximum dose is two tablets once daily. In general the antihypertensive effect is attained within three weeks after initiation of therapy. HYZAAR should not be initiated in patients who are intravascularly volume-depleted (e.g. those treated with high-dose diuretics). Page 2 of 17 Reduction in the Risk of Cardiovascular Morbidity and Mortality in Hypertensive Patients with Left Ventricular Hypertrophy The usual starting dose is 50 mg of losartan once daily. If goal blood pressure is not reached with losartan 50 mg, therapy should be titrated using a combination of losartan and a low dose of hydrochlorothiazide (12.5 mg*) and, if needed, the dose should then be increased to losartan 100 mg and hydrochlorothia Perskaitykite visą dokumentą