HORAMINE TABLET 4MG

Šalis: Malaizija

kalba: anglų

Šaltinis: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Veiklioji medžiaga:

CHLORPHENIRAMINE MALEATE

Prieinama:

HOVID BERHAD

INN (Tarptautinis Pavadinimas):

CHLORPHENIRAMINE MALEATE

Vienetai pakuotėje:

1000 Tablets; 100 Tablets; 100 Tablets

Pagaminta:

HOVID BERHAD

Pakuotės lapelis

Please refer to E12.

Prekės savybės

HORAMINE
DESCRIPTION
Horamine Tablet: Round, yellow uncoated tablet, shallow convex faces;
“HD” embossed and scored on the same face.
Horamine Syrup: Red, raspberry flavoured viscous liquid.
COMPOSITION
Horamine Tablet: Each tablet contains Chlorpheniramine Maleate 4 mg.
Horamine Syrup: Each 5 ml contains Chlorpheniramine Maleate 4 mg.
PHARMACODYNAMICS
Chlorpheniramine acts by competing with histamine for H1-receptor
sites on effector cells, thus preventing responses mediated by
histamine. Its antimuscarinic actions will provide a drying effect on
the nasal mucosa.
PHARMACOKINETICS
Chlorpheniramine is readily absorbed after oral administration,
metabolised in the liver and excreted mainly in the urine. It is
widely
distributes throughout the body tissues and appears to be subjected to
enterohepatic circulation. It is metabolized in the liver to form
polar and non-polar metabolites.
INDICATIONS
For symptomatic treatment of:
Allergic or vasomotor rhinitis, hay fever, urticaria, angioneurotic
oedema, sensitivity reactions and other itching skin conditions
including pruritus ani, pruritus vulvae, pruritus of drug rashes,
contact dermatitis and insect bites.
CONTRAINDICATIONS
•
Avoid in patients known to be hypersensitive to antihistamines.
•
Use is not recommended in nursing mothers and in children below 6
years of age.
WARNING AND PRECAUTIONS
This medication may cause drowsiness in some patients.
Caution when driving or operating machinery.
Avoid alcoholic beverages.
When used for treatment of cough and cold;
(a) Not to be used in children less than 2 years of age
(b) To be used with caution and doctor’s / pharmacist’s advice in
children 2 to 6 years of age.
PREGNANCY AND LACTATION
Pregnancy: The risk-benefit must be considered, although no
association between any fetal abnormalities has been formed with
chlorpheniramine.
Lactation: Small amount of chlorpheniramine are excreted in breast
milk. Due to the higher risk of adverse effects of antihistamines in
infants, the use of chlorpheniramine is not recom