Bredicon 75mcg Tablet

Šalis: Malaizija

kalba: anglų

Šaltinis: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Veiklioji medžiaga:

DESOGESTREL

Prieinama:

Vitamode Sdn.bhd

INN (Tarptautinis Pavadinimas):

DESOGESTREL

Vienetai pakuotėje:

1X28tablet Tablets

Pagaminta:

RENATA LIMITED

Prekės savybės

1
BREDICON
® 75MCG TABLET
(DESOGESTREL 75 MCG)
COMPOSITION:
Each tablet contains: Desogestrel 75 microgram
DESCRIPTION:
White colored tablet, Round Flat Bevel Edge, one side contains logo
“B/75” and other
side plain.
PHARMACODYNAMICS:
This medicine is a type of hormonal contraceptive commonly known as
the “mini pill” or
progestogen-only pill (POP). It contains the active ingredient
desogestrel , which is a
synthetic progestogen, similar to the natural progestogen produced by
the body.
Desogestrel is thought to act as a contraceptive primarily by
preventing the release of an
egg from the ovary (Ovulation). It also acts by increasing the
thickness of the natural
mucus at the neck of the womb, making it more difficult for sperm to
cross from the
vagina into the womb. By preventing sperm entering the womb,
successful fertilization of
any eggs that are released is less likely.
Desogestrel also acts to change the quality of the womb lining
(endometrium). This
prevents the successful implantation of any fertilized eggs onto the
wall of the womb,
thereby preventing pregnancy.
The progesterone only-pill should be taken continuously every day,
unlike combined
pills, which are usually taken every day for three weeks, followed by
a pill-free week.
This progesterone-only pill should be taken continuously at the same
time evry day for it
to be effective at the preventing pregnancy.
MECHANISM OF ACTION:
Desogestrel is a progestogen structurally related to levonorgestrel
that has been shown to
reliably inhibit ovulation. After oral administration, it undergoes
oxidative transformation
in the intestinal mucosa and liver to form its active metabolite,
3-keto-desogestrel.
2
PHARMACOKINETICS:
ABSORPTION:
After
oral
dosing
of
Bredicon,
Desogestrel
is
rapidly
absorbed
and
converted into its biologically active metabolite etonogestrel (ENG).
Under steady-state
conditions, peak serum levels are reached 1.8 hrs after tablet intake
and the absolute
bioavailability of ENG is approximately 70%.
DISTRIBUTION:
ENG is 95.5-99% bound t