ALLERYL SYRUP 4MG5ML

Šalis: Malaizija

kalba: anglų

Šaltinis: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Veiklioji medžiaga:

CHLORPHENIRAMINE MALEATE

Prieinama:

IDAMAN PHARMA MANUFACTURING SDN BHD

INN (Tarptautinis Pavadinimas):

CHLORPHENIRAMINE MALEATE

Vienetai pakuotėje:

60 ml

Pagaminta:

IDAMAN PHARMA MANUFACTURING SDN BHD

Pakuotės lapelis

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
_ _
ALLERYL SYRUP 4MG/5ML
Chlorpheniramine Maleate (4mg/5ml)
1
WHAT IS IN THIS LEAFLET
1.
What Alleryl Syrup 4mg/5ml is used
for
2.
How it works
3.
Before
you
use
Alleryl
Syrup
4mg/5ml
4.
How to use Alleryl Syrup 4mg/5ml
5.
While you are using it
6.
Side effects
7.
Storage
and
Disposal
of
Alleryl
Syrup 4mg/5ml
8.
Product Description
9.
Product
Registration
Holder
&
Manufacturer
10.
Date of Revision
WHAT ALLERYL SYRUP 4MG/5ML IS USED
FOR
Alleryl
Syrup
4mg/5ml
belongs
to
a
group of medicines called antihistamines.
Alleryl
Syrup
4mg/5ml
contains
chlorpheniramine maleate which is used
to treat the following:
•
symptomatic treatment of allergic
rhinitis
(inflammation
of
the
membranes
inside
of
the
nose),
vasomotor
rhinitis
(non-allergic),
antihistamine
and
allergic
conjunctivitis (eye inflammation) due
to inhalant allergens and foods.
•
symptomatic treatment of skin itching
associated with allergic reactions and
of mild, uncomplicated symptoms of
urticaria (a red raised, itchy rash on the
skin)
and
angioedema
(swelling
of
deeper skin tissues).
•
as
combination
with
a
decongestant
(Pseudoephedrine)
for
the
temporary
relief
of
nasal
and
sinus
congestion
associated with the common cold and
allergic rhinitis.
HOW IT WORKS
Alleryl
Syrup
4mg/5ml
acts
as
antihistamine which works by blocking a
histamine that causes the symptoms of
allergies.
It also possesses anticholinergic activity
whereby
it
blocks
the
acetylcholine
which
cause
involuntary
muscle
movement.
BEFORE YOU USE ALLERYL SYRUP 4MG/5ML
_-When you must not use it _
Do not use Alleryl Syrup 4mg/5ml if you
are:
•
allergic to Chlorpheniramine maleate
or any ingredients stated at the end of
this leaflet.
•
taking Monoamine Oxidase Inhibitors
(MAOIs) or been treated with MAOIs
within last fourteen days.
•
having
rare
hereditary
problems
of
_fructose_
intolerance,
_glucose-galactose_
malabsorption
or
_sucrose-isomaltase_
insufficiency.
•
concurrent
used
with
other
antihistamine
products
containing
cough and

Prekės savybės

8.4.2022
-
BLACK
MS ZAKIAH
MALA
IDAMAN PHARMA MANUFACTURING SDN BHD
ALLERYL SYRUP 4MG/5ML
W: 210MM X H: 297MM
SMPO 050
Thunder Print Sdn. Bhd.
(374290-X)
6463, Lorong Ayam Didik 2, Taman Ria Jaya Light Industrial Park,
08000 Sg. Petani, Kedah Darul Aman. Tel : [phone] Fax : 04-4424
005
LT-305.00
MATERIAL CODE:
ALLERYL SYRUP 4MG/5ML
DESCRIPTION
Colourless to yellowish clear syrup, sweet, pleasant and slightly
sourish after taste.
COMPOSITION
_EACH 5ML OF THE SYRUP CONTAINS: _
Chlorpheniramine Maleate 4 mg
_Preservative: _Sodium Benzoate 5 mg
PHARMACODYNAMICS
ATC code: R06AB02
C
hlorpheniramine
Maleate
is
a
potent
antihistamine
(H1-
antagonist). Antihistamines diminish or abolish the actions of
histamine in the body by competitive reversible blockade of
histamine
H1-receptor
sites
on
tissues.
Chlorpheniramine
Maleate also has anticholinergic activity.
Antihistamines prevent the migration of inflammatory mediators
and the release of histamine, prostaglandins and leukotrienes.
The actions of Chlorpheniramine Maleate include inhibition of
histamine
on
smooth
muscle,
capillary
permeability
and
reduction of oedema and wheal in hypersensitivity reactions
such as allergy and anaphylaxis.
PHARMACOKINETICS
Following oral administration, Chlorpheniramine Maleate is well
absorbed from the gastro- intestinal tract. The effects develop
within 30 minutes, are maximal within 1 to 2 hours and last 4 to
6 hours. The plasma half-life is estimated to be 12 to 15 hours.
Chlorpheniramine Maleate is metabolised
to monodesmethyl
and didesmethyl derivatives. About 22% of an oral dose is
excreted unchanged in the urine.
INDICATIONS
1)
Symptomatic treatment of perennial and seasonal allergic
rhinitis, vasomotor rhinitis, antihistamines including hay
fever and allergic conjunctivitis due to inhalant allergens
and foods.
2)
Symptomatic treatment of pruritus associated with allergic
reactions
and
of
mild,
uncomplicated
allergic
skin
manifestations of urticaria and angioedema.
3)
May
be
used
in
combination
with
a
decongestant
(Pseudoephedri