Maa: Malesia
Kieli: englanti
Lähde: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
CHLORPHENIRAMINE MALEATE
IDAMAN PHARMA MANUFACTURING SDN BHD
CHLORPHENIRAMINE MALEATE
60 ml
IDAMAN PHARMA MANUFACTURING SDN BHD
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ _ _ ALLERYL SYRUP 4MG/5ML Chlorpheniramine Maleate (4mg/5ml) 1 WHAT IS IN THIS LEAFLET 1. What Alleryl Syrup 4mg/5ml is used for 2. How it works 3. Before you use Alleryl Syrup 4mg/5ml 4. How to use Alleryl Syrup 4mg/5ml 5. While you are using it 6. Side effects 7. Storage and Disposal of Alleryl Syrup 4mg/5ml 8. Product Description 9. Product Registration Holder & Manufacturer 10. Date of Revision WHAT ALLERYL SYRUP 4MG/5ML IS USED FOR Alleryl Syrup 4mg/5ml belongs to a group of medicines called antihistamines. Alleryl Syrup 4mg/5ml contains chlorpheniramine maleate which is used to treat the following: • symptomatic treatment of allergic rhinitis (inflammation of the membranes inside of the nose), vasomotor rhinitis (non-allergic), antihistamine and allergic conjunctivitis (eye inflammation) due to inhalant allergens and foods. • symptomatic treatment of skin itching associated with allergic reactions and of mild, uncomplicated symptoms of urticaria (a red raised, itchy rash on the skin) and angioedema (swelling of deeper skin tissues). • as combination with a decongestant (Pseudoephedrine) for the temporary relief of nasal and sinus congestion associated with the common cold and allergic rhinitis. HOW IT WORKS Alleryl Syrup 4mg/5ml acts as antihistamine which works by blocking a histamine that causes the symptoms of allergies. It also possesses anticholinergic activity whereby it blocks the acetylcholine which cause involuntary muscle movement. BEFORE YOU USE ALLERYL SYRUP 4MG/5ML _-When you must not use it _ Do not use Alleryl Syrup 4mg/5ml if you are: • allergic to Chlorpheniramine maleate or any ingredients stated at the end of this leaflet. • taking Monoamine Oxidase Inhibitors (MAOIs) or been treated with MAOIs within last fourteen days. • having rare hereditary problems of _fructose_ intolerance, _glucose-galactose_ malabsorption or _sucrose-isomaltase_ insufficiency. • concurrent used with other antihistamine products containing cough and Lue koko asiakirja
8.4.2022 - BLACK MS ZAKIAH MALA IDAMAN PHARMA MANUFACTURING SDN BHD ALLERYL SYRUP 4MG/5ML W: 210MM X H: 297MM SMPO 050 Thunder Print Sdn. Bhd. (374290-X) 6463, Lorong Ayam Didik 2, Taman Ria Jaya Light Industrial Park, 08000 Sg. Petani, Kedah Darul Aman. Tel : 04-4418 005 Fax : 04-4424 005 LT-305.00 MATERIAL CODE: ALLERYL SYRUP 4MG/5ML DESCRIPTION Colourless to yellowish clear syrup, sweet, pleasant and slightly sourish after taste. COMPOSITION _EACH 5ML OF THE SYRUP CONTAINS: _ Chlorpheniramine Maleate 4 mg _Preservative: _Sodium Benzoate 5 mg PHARMACODYNAMICS ATC code: R06AB02 C hlorpheniramine Maleate is a potent antihistamine (H1- antagonist). Antihistamines diminish or abolish the actions of histamine in the body by competitive reversible blockade of histamine H1-receptor sites on tissues. Chlorpheniramine Maleate also has anticholinergic activity. Antihistamines prevent the migration of inflammatory mediators and the release of histamine, prostaglandins and leukotrienes. The actions of Chlorpheniramine Maleate include inhibition of histamine on smooth muscle, capillary permeability and reduction of oedema and wheal in hypersensitivity reactions such as allergy and anaphylaxis. PHARMACOKINETICS Following oral administration, Chlorpheniramine Maleate is well absorbed from the gastro- intestinal tract. The effects develop within 30 minutes, are maximal within 1 to 2 hours and last 4 to 6 hours. The plasma half-life is estimated to be 12 to 15 hours. Chlorpheniramine Maleate is metabolised to monodesmethyl and didesmethyl derivatives. About 22% of an oral dose is excreted unchanged in the urine. INDICATIONS 1) Symptomatic treatment of perennial and seasonal allergic rhinitis, vasomotor rhinitis, antihistamines including hay fever and allergic conjunctivitis due to inhalant allergens and foods. 2) Symptomatic treatment of pruritus associated with allergic reactions and of mild, uncomplicated allergic skin manifestations of urticaria and angioedema. 3) May be used in combination with a decongestant (Pseudoephedri Lue koko asiakirja