환자 정보 전단
Quinine Dihydrochloride 6%
Page 1 of 3
_ _
_Version 05 _
QUININE DIHYDROCHLORIDE
6% STERILE CONCENTRATE
600 MG IN 10 ML
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Quinine
Dihydrochloride 6% Sterile
Concentrate. It does not contain all the
available information. It does not take
the place of talking to your doctor.
All medicines have risks and benefits
.
Your doctor has weighed the risks of
you being given Quinine
Dihydrochloride 6% Sterile
Concentrate against the benefits they
expect it will have for you.
IF YOU HAVE ANY CONCERNS ABOUT
BEING GIVEN THIS MEDICINE, ASK YOUR
DOCTOR.
KEEP THIS LEAFLET.
You may need to read it again.
WHAT QUININE
DIHYDROCHLORIDE 6%
STERILE CONCENTRATE IS
USED FOR
QUININE DIHYDROCHLORIDE 6% STERILE
CONCENTRATE IS A CONCENTRATED
SOLUTION AND MUST BE DILUTED BEFORE
USE.
This medicine is used for the treatment
of severe malaria or when the patient is
unable to take medication by mouth.
It is also used in the treatment of
Babesiosis, a rare disease caused by an
infection carried by ticks.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY QUININE
DIHYDROCHLORIDE 6% STERILE
CONCENTRATE HAS BEEN PRESCRIBED FOR
YOU.
Your doctor may have prescribed it for
another reason.
BEFORE YOU ARE GIVEN
QUININE
DIHYDROCHLORIDE 6%
STERILE CONCENTRATE
_WHEN YOU MUST NOT BE GIVEN _
_IT _
YOU MUST NOT BE GIVEN QUININE
DIHYDROCHLORIDE 6% STERILE
CONCENTRATE IF YOU HAVE AN ALLERGY TO
QUININE OR QUINIDINE.
Some of the symptoms of an allergic
reaction may include:
•
shortness of breath
•
wheezing or difficulty breathing
•
swelling of the face, lips, tongue
or other parts of the body
•
rash,
전체 문서 읽기
제품 특성 요약
PRODUCT INFORMATION
Quinine Dihydrochloride 6% Sterile
Concentrate 600 mg in 10 mL
Product Information- Quinine Dihydrochloride 6% Sterile Concentrate 600 mg in 10 mL
Page 1
Version 08
QUININE DIHYDROCHLORIDE 6% Sterile Concentrate
600 mg in 10 mL
DILUTE BEFORE ADMINISTRATION
NAME OF THE MEDICINE
Quinine Dihydrochloride BP
Chemical Name: - (8S, 9R)-6’-methoxycinchonan-9-ol dihydrochloride.
The molecular weight of the compound is 397.3 and the CAS registry number is 60-93-5. The molecular formula is C
20
H
24
N
2
O
2
, 2HCl.
Structural Formula:
DESCRIPTION
QUININE DIHYDROCHLORIDE 6% STERILE CONCENTRATE 600 mg in 10 mL is a faint straw coloured sterile solution containing
600 mg quinine dihydrochloride in 10 mL of water for injections. The solution should be diluted before administration and contains no
antimicrobial preservative. QUININE DIHYDROCHLORIDE 6% STERILE CONCENTRATE 600 mg in 10 mL should be used in one patient
on one occasion only and unused solution should be discarded.
PHARMACOLOGY
Pharmacodynamics
The exact mechanism of action of quinine in malaria is uncertain, but its actions appear to interfere with the function of plasmodial DNA. It
inhibits protein synthesis by preventing strand separation and therefore DNA replication and transcription to RNA. Its primary action is
schizonticidal, and no lethal effect is exerted on sporozoites or pre-erythrocytic tissue forms. It is gametocytocidal for P vivax and P
malariae.
CNS: Quinine has slight analgesic and antipyretic activity. It has indifferent action on fevers except malarial fever.
Cardiovascular
전체 문서 읽기
환자 정보 전단 