Nazione: Australia
Lingua: inglese
Fonte: Department of Health (Therapeutic Goods Administration)
Quinine dihydrochloride
Phebra Pty Ltd
Medicine Registered
Quinine Dihydrochloride 6% Page 1 of 3 _ _ _Version 05 _ QUININE DIHYDROCHLORIDE 6% STERILE CONCENTRATE 600 MG IN 10 ML CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Quinine Dihydrochloride 6% Sterile Concentrate. It does not contain all the available information. It does not take the place of talking to your doctor. All medicines have risks and benefits . Your doctor has weighed the risks of you being given Quinine Dihydrochloride 6% Sterile Concentrate against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT BEING GIVEN THIS MEDICINE, ASK YOUR DOCTOR. KEEP THIS LEAFLET. You may need to read it again. WHAT QUININE DIHYDROCHLORIDE 6% STERILE CONCENTRATE IS USED FOR QUININE DIHYDROCHLORIDE 6% STERILE CONCENTRATE IS A CONCENTRATED SOLUTION AND MUST BE DILUTED BEFORE USE. This medicine is used for the treatment of severe malaria or when the patient is unable to take medication by mouth. It is also used in the treatment of Babesiosis, a rare disease caused by an infection carried by ticks. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY QUININE DIHYDROCHLORIDE 6% STERILE CONCENTRATE HAS BEEN PRESCRIBED FOR YOU. Your doctor may have prescribed it for another reason. BEFORE YOU ARE GIVEN QUININE DIHYDROCHLORIDE 6% STERILE CONCENTRATE _WHEN YOU MUST NOT BE GIVEN _ _IT _ YOU MUST NOT BE GIVEN QUININE DIHYDROCHLORIDE 6% STERILE CONCENTRATE IF YOU HAVE AN ALLERGY TO QUININE OR QUINIDINE. Some of the symptoms of an allergic reaction may include: • shortness of breath • wheezing or difficulty breathing • swelling of the face, lips, tongue or other parts of the body • rash, Leggi il documento completo
PRODUCT INFORMATION Quinine Dihydrochloride 6% Sterile Concentrate 600 mg in 10 mL Product Information- Quinine Dihydrochloride 6% Sterile Concentrate 600 mg in 10 mL Page 1 Version 08 QUININE DIHYDROCHLORIDE 6% Sterile Concentrate 600 mg in 10 mL DILUTE BEFORE ADMINISTRATION NAME OF THE MEDICINE Quinine Dihydrochloride BP Chemical Name: - (8S, 9R)-6’-methoxycinchonan-9-ol dihydrochloride. The molecular weight of the compound is 397.3 and the CAS registry number is 60-93-5. The molecular formula is C 20 H 24 N 2 O 2 , 2HCl. Structural Formula: DESCRIPTION QUININE DIHYDROCHLORIDE 6% STERILE CONCENTRATE 600 mg in 10 mL is a faint straw coloured sterile solution containing 600 mg quinine dihydrochloride in 10 mL of water for injections. The solution should be diluted before administration and contains no antimicrobial preservative. QUININE DIHYDROCHLORIDE 6% STERILE CONCENTRATE 600 mg in 10 mL should be used in one patient on one occasion only and unused solution should be discarded. PHARMACOLOGY Pharmacodynamics The exact mechanism of action of quinine in malaria is uncertain, but its actions appear to interfere with the function of plasmodial DNA. It inhibits protein synthesis by preventing strand separation and therefore DNA replication and transcription to RNA. Its primary action is schizonticidal, and no lethal effect is exerted on sporozoites or pre-erythrocytic tissue forms. It is gametocytocidal for P vivax and P malariae. CNS: Quinine has slight analgesic and antipyretic activity. It has indifferent action on fevers except malarial fever. Cardiovascular Leggi il documento completo