국가: 미국
언어: 영어
출처: NLM (National Library of Medicine)
NEOMYCIN SULFATE (UNII: 057Y626693) (NEOMYCIN - UNII:I16QD7X297), ISOFLUPREDONE ACETATE (UNII: 55P9TUL75S) (ISOFLUPREDONE - UNII:HYS0B45Z2S), TETRACAINE HYDROCHLORIDE (UNII: 5NF5D4OPCI) (TETRACAINE - UNII:0619F35CGV)
Zoetis Inc.
TOPICAL
PRESCRIPTION
NEO-PREDEF with Tetracaine Powder is indicated in the treatment or adjunctive therapy of certain ear and skin conditions in dogs, cats and horses caused by or associated with neomycin-susceptible organisms and/or allergy. In addition, it is indicated as superficial dressing applied to minor cuts, wounds, lacerations, abrasions, and for post-surgical application where reduction of pain and inflammatory response is deemed desirable. NEO-PREDEF with Tetracaine Powder may be used as a dusting powder following amputation of tails, claws, and dew-claws; following ear trimming and castrating; and following such surgical procedure as ovariohysterectomies. Applied superficially, it has been used successfully in the treatment of acute otitis externa in dogs, acute moist dermatitis and interdigital dermatitis in the dog, and as a dusting powder to various minor cuts, lacerations, and abrasions in the horse, cat and dog.
NEO-PREDEF with Tetracaine Powder is available in 15 gram plastic insufflator bottles. Because of the hygroscopic properties of neomycin sulfate, this bottle should be stored in a dry place. The cap should be replaced when the bottle is not in use. This puffer bottle has been designed to permit dusting when held in any position. Protecting the outlet from moisture will aid in assuring proper function; therefore, the tip should not be allowed to come in contact with moist membranes or weeping surfaces.
New Animal Drug Application
NEO-PREDEF WITH TETRACAINE- NEOMYCIN SULFATE, ISOFLUPREDONE ACETATE, AND TETRACAINE HYDROCHLORIDE POWDER ZOETIS INC. ---------- NEO-PREDEF WITH TETRACAINE POWDER (NEOMYCIN SULFATE, ISOFLUPREDONE ACETATE, AND TETRACAINE HYDROCHLORIDE TOPICAL POWDER) FOR USE IN ANIMALS ONLY FOR TOPICAL EAR AND SKIN USE IN DOGS, CATS AND HORSES CAUTION Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION NEO-PREDEF with Tetracaine Powder contains in each gram neomycin sulfate, 5 mg (equivalent to 3.5 mg neomycin); isoflupredone acetate, 1 mg; tetracaine hydrochloride, 5 mg; myristyl-gamma-picolinium chloride (as a preservative); and lactose hydrous. Because of the prompt, potent, and specific actions of the individual components, this combination is well suited for the treatment of certain ear and skin conditions occurring in dogs, cats and horses. ADVANTAGES OF NEO-PREDEF WITH TETRACAINE 1. Highly potent anti-inflammatory effect of isoflupredone acetate. 2. Wide-spectrum bactericidal effect of neomycin. 3. Rapid anesthetic effect of tetracaine. 4. Prompt relief of symptoms. 5. Reduces further self-inflicted trauma. 6. Ease of application. 7. Adherent to moist surfaces. ISOFLUPREDONE ACETATE Isoflupredone acetate markedly inhibits inflammatory reaction through its controlling influence on connective tissue and vascular components. Topically applied isoflupredone acetate is usually rapidly effective. In otitis externa, wounds of the concha, ulcerations of the ear flaps, and irritated lesions of the skin, the inflammatory response may also be effectively inhibited by isoflupredone acetate. Chronic conditions respond more slowly and relapses are more frequent. NEOMYCIN Neomycin is an antibiotic substance derived from cultures of the soil organism _Streptomyces fradiae._ Its antimicrobial range includes both gram-positive and gram-negative organisms commonly responsible for or associated with otic infections, such as staphylococci, streptococci, _Escherichia coli., Aerobacter_ _aerogene 전체 문서 읽기