NEO-PREDEF WITH TETRACAINE- neomycin sulfate, isoflupredone acetate, and tetracaine hydrochloride powder

Maa: Yhdysvallat

Kieli: englanti

Lähde: NLM (National Library of Medicine)

Aktiivinen ainesosa:

NEOMYCIN SULFATE (UNII: 057Y626693) (NEOMYCIN - UNII:I16QD7X297), ISOFLUPREDONE ACETATE (UNII: 55P9TUL75S) (ISOFLUPREDONE - UNII:HYS0B45Z2S), TETRACAINE HYDROCHLORIDE (UNII: 5NF5D4OPCI) (TETRACAINE - UNII:0619F35CGV)

Saatavilla:

Zoetis Inc.

Antoreitti:

TOPICAL

Prescription tyyppi:

PRESCRIPTION

Käyttöaiheet:

NEO-PREDEF with Tetracaine Powder is indicated in the treatment or adjunctive therapy of certain ear and skin conditions in dogs, cats and horses caused by or associated with neomycin-susceptible organisms and/or allergy. In addition, it is indicated as superficial dressing applied to minor cuts, wounds, lacerations, abrasions, and for post-surgical application where reduction of pain and inflammatory response is deemed desirable. NEO-PREDEF with Tetracaine Powder may be used as a dusting powder following amputation of tails, claws, and dew-claws; following ear trimming and castrating; and following such surgical procedure as ovariohysterectomies. Applied superficially, it has been used successfully in the treatment of acute otitis externa in dogs, acute moist dermatitis and interdigital dermatitis in the dog, and as a dusting powder to various minor cuts, lacerations, and abrasions in the horse, cat and dog.

Tuoteyhteenveto:

NEO-PREDEF with Tetracaine Powder is available in 15 gram plastic insufflator bottles. Because of the hygroscopic properties of neomycin sulfate, this bottle should be stored in a dry place. The cap should be replaced when the bottle is not in use. This puffer bottle has been designed to permit dusting when held in any position. Protecting the outlet from moisture will aid in assuring proper function; therefore, the tip should not be allowed to come in contact with moist membranes or weeping surfaces.

Valtuutuksen tilan:

New Animal Drug Application

Valmisteyhteenveto

NEO-PREDEF WITH TETRACAINE- NEOMYCIN SULFATE, ISOFLUPREDONE ACETATE,
AND TETRACAINE
HYDROCHLORIDE POWDER
ZOETIS INC.
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NEO-PREDEF
WITH TETRACAINE POWDER
(NEOMYCIN SULFATE, ISOFLUPREDONE ACETATE, AND TETRACAINE HYDROCHLORIDE
TOPICAL POWDER)
FOR USE IN ANIMALS ONLY
FOR TOPICAL EAR AND SKIN USE IN DOGS, CATS AND HORSES
CAUTION
Federal (USA) law restricts this drug to use by or on the order of a
licensed veterinarian.
DESCRIPTION
NEO-PREDEF with Tetracaine Powder contains in each gram neomycin
sulfate, 5 mg (equivalent to 3.5
mg neomycin); isoflupredone acetate, 1 mg; tetracaine hydrochloride, 5
mg; myristyl-gamma-picolinium
chloride (as a preservative); and lactose hydrous. Because of the
prompt, potent, and specific actions of
the individual components, this combination is well suited for the
treatment of certain ear and skin
conditions occurring in dogs, cats and horses.
ADVANTAGES OF NEO-PREDEF WITH TETRACAINE
1. Highly potent anti-inflammatory effect of isoflupredone acetate.
2. Wide-spectrum bactericidal effect of neomycin.
3. Rapid anesthetic effect of tetracaine.
4. Prompt relief of symptoms.
5. Reduces further self-inflicted trauma.
6. Ease of application.
7. Adherent to moist surfaces.
ISOFLUPREDONE ACETATE
Isoflupredone acetate markedly inhibits inflammatory reaction through
its controlling influence on
connective tissue and vascular components. Topically applied
isoflupredone acetate is usually rapidly
effective. In otitis externa, wounds of the concha, ulcerations of the
ear flaps, and irritated lesions of
the skin, the inflammatory response may also be effectively inhibited
by isoflupredone acetate. Chronic
conditions respond more slowly and relapses are more frequent.
NEOMYCIN
Neomycin is an antibiotic substance derived from cultures of the soil
organism _Streptomyces fradiae._ Its
antimicrobial range includes both gram-positive and gram-negative
organisms commonly responsible
for or associated with otic infections, such as staphylococci,
streptococci, _Escherichia coli., Aerobacter_
_aerogene