UREA NAIL gel

国: アメリカ合衆国

言語: 英語

ソース: NLM (National Library of Medicine)

有効成分:

UREA (UNII: 8W8T17847W) (UREA - UNII:8W8T17847W)

から入手可能:

H2-Pharma, LLC

INN（国際名）:

UREA

構図:

UREA 450 mg in 1 mL

処方タイプ:

PRESCRIPTION DRUG

認証ステータス:

unapproved drug other

製品の特徴

UREA NAIL- UREA GEL
H2-PHARMA, LLC
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
----------
45% UREA NAIL GEL
IN A VEHICLE CONTAINING MENTHOL, CAMPHOR AND EUCALYPTUS OIL
RX ONLY
FOR EXTERNAL USE ONLY. NOT FOR OPHTHALMIC USE.
DESCRIPTION
45% Urea Nil Gel is a keratolytic emollient, which is a gentle, yet
potent, tissue softener for nails
and/or skin. Each gram of 45% Urea Nail Gel contains: 45% urea. Other
ingredients: camphor, disodium
EDTA, eucalyptus oil, hydroxyethylcellulose, menthol, propylene
glycol, and purified water.
Urea is a diamide of carbonic acid with the following chemical
structure:
CLINICAL PHARMACOLOGY
Urea gently dissolves the intercellular matrix, which results in
loosening the horny layer of skin and
shedding scaly skin at regular intervals, thereby softening
hyperkeratotic areas. Urea also hydrates and
gently dissolves the intercellular matrix of the nail plate, which can
result in the softening and eventual
removal of devitalized nail plate tissue.
PHARMACOKINETICS
The mechanism of action of topically applied Urea is not yet known.
INDICATIONS AND USES
45% Urea Nail Gel is indicated for use in the topical treatment for
debridement and promotion of normal
healing of hyperkeratotic surface lesions, particularly where healing
is retarded by local infection,
necrotic tissue, fibrinous or purulent debris or eschar. Urea is
useful for the treatment of hyperkeratotic
conditions such as dry, rough skin, dermatitis, psoriasis, xerosis,
ichthyosis, eczema, keratosis,
keratoderma, corns and calluses, as well as damaged, devitalized and
ingrown nails.
CONTRAINDICATIONS
Known hypersensitivity to any of the listed ingredients.
WARNINGS
For external use only. Avoid contact with eyes, lips or mucus
membranes. Temporary stinging, burning,
itching, or irritation may occur and normally disappear on
discontinuation of the medication.
PRECAUTIONS
This medication is to be us