TENUATE DOSPAN TABLET (EXTENDED-RELEASE)

国: カナダ

言語: 英語

ソース: Health Canada

有効成分:

DIETHYLPROPION HYDROCHLORIDE

から入手可能:

SANOFI-AVENTIS CANADA INC

ATCコード:

A08AA03

INN（国際名）:

AMFEPRAMONE

投薬量:

75MG

医薬品形態:

TABLET (EXTENDED-RELEASE)

構図:

DIETHYLPROPION HYDROCHLORIDE 75MG

投与経路:

ORAL

パッケージ内のユニット:

100

処方タイプ:

Schedule G (CDSA IV)

治療領域:

Amphetamine Derivatives

製品概要:

Active ingredient group (AIG) number: 0102499001; AHFS:

認証ステータス:

CANCELLED POST MARKET

承認日:

2009-01-31

製品の特徴

PRODUCT MONOGRAPH
TENUATE
®
(diethylpropion hydrochloride)
Tablets, 25 mg
TENUATE
®
DOSPAN
®
(diethylpropion hydrochloride)
Continuous Release Tablets, 75 mg
Anorexiant
sanofi-aventis Canada Inc.
Date of Preparation:
2150 St. Elzear Blvd. West
March 23, 2006
Laval, Quebec H7L 4A8
Submission Control No. 104730
s-a Version 1.0 dated
1
PRODUCT MONOGRAPH
TENUATE
®
(diethylpropion hydrochloride)
Tablets, 25 mg
TENUATE
®
DOSPAN
®
(diethylpropion hydrochloride)
Continuous Release Tablets, 75 mg
THERAPEUTIC CLASSIFICATION
Anorexiant
ACTION
TENUATE
®
(diethylpropion hydrochloride) is a psychomotor stimulant with
anorectic,
sympathomimetic and other effects similar to those of amphetamines. As
with all other
drugs of this class in which the phenomenon has been studied, the
initial rate of weight loss
decreases until a plateau is reached; a regain of weight thereafter
even though drug
administration is continued has been reported. As with similar drugs,
rebound weight gain
also may occur after discontinuation of TENUATE
®
.
INDICATIONS AND CLINICAL USE
A psychomotor stimulant used as an adjunct in the short-term (i.e. a
few weeks) to
continued dietary treatment in the medical management of obesity, in
patients who have
not responded to an appropriate weight reducing regimen (diet and/or
exercise) alone.
TENUATE
®
is recommended only for obese patients with an initial body mass index
$
30
kg/m
2
, or
$
27 kg/m
2
in the presence of other risk factors (e.g. hypertension, diabetes,
hyperlipidaemia).
Below is a chart of Body Mass Index (BMI) based on various heights and
weights. BMI is
calculated by taking the patient’s weight, in kilograms, divided by
the patient’s height in
meters and squared. Metric conversions are as follows:
2
S
Pounds(lbs)/2.2 = kilograms (kg)
S
Feet (ft) x 0.3048 = meters (m)
S
Inches x 0.0254 = meters (m)
BODY MASS INDEX (BMI), kg/m
2
Height (feet, inches)
Weight
(pounds)
5'0"
5'3"
5'6"
5'9"
6'0"
6'3"
140
27
25
23
21
19
18
150
29
27
24
22
20
19
160
31
28
26
24
22
20
170
33
30
28
25
23
21
180