国: マレーシア
言語: 英語
ソース: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
ENALAPRIL MALEATE
ORGANON MALAYSIA SDN. BHD.
ENALAPRIL MALEATE
30Tablet Tablets
Organon Pharma (UK) Limited
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ RENITEC ® Enalapril Maleate (5mg, 10mg, 20mg) Copyright 2021 Organon group of companies. All rights reserved. WHAT IS IN THIS LEAFLET 1. What _RENITEC _ is used for 2. How _RENITEC _ works 3. Before you take _RENITEC_ 4. How to take _RENITEC_ _5._ _ _ While you are taking _ _ _RENITEC _ 6. Side effects 7. Storage and disposal of _RENITEC _ 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT _RENITEC _IS USED FOR _RENITEC _ is a tablet. _RENITEC _ is a medication that belongs to the group of medicine called angiotensin converting enzyme inhibitors, (ACE inhibitors). Your doctor has prescribed _RENITEC _ to treat your hypertension (high blood pressure) or heart failure (weakening of heart function). _RENITEC _ is also used for the prevention of symptomatic heart failure. In many patients with heart failure who have symptoms, _RENITEC _ slows the worsening of heart failure, reduces the need to go to the hospital as a result of heart failure, and helps some of these patients to live longer. In many patients with early stage heart failure prior to the development of symptoms, _RENITEC _ helps to prevent the weakening of heart function and to slow the development of symptoms (for instance, shortness of breath, tiredness after light physical activity such as walking, or swelling of the ankles and feet). These patients may be less likely to have hospital stays as a result of heart failure. By taking _RENITEC_ , some heart failure patients may lessen their risk of heart attack. HOW _RENITEC _WORKS _RENITEC _ works by widening your blood vessels to make it easier for the heart to pump blood to all parts of your body. This helps to reduce high blood pressure. In many patients with heart failure, _RENITEC _ will help the heart to function better. You have high blood pressure or hypertension if your blood pressure stays high even when you are calm and relaxed. High blood pressure develops when the blood vessels tighten, making it 完全なドキュメントを読む
RENITEC (enalapril maleate/enalaprilat) [Tablets] S-LPC-OG0421-MF-102020-Malaysia Copyright 2021 Organon group of companies. All rights reserved. LOCAL PHYSICIANS CIRCULAR Tablets RENITEC® Oral (enalapril maleate) RENITEC ® (enalapril maleate) is the maleate salt of enalapril, a derivative of two amino-acids, L-alanine and L-proline. Following oral administration, enalapril is rapidly absorbed and then hydrolyzed to enalaprilat, which is a highly specific, long-acting, non-sulphydryl angiotensin converting enzyme inhibitor. RENITEC is indicated in the treatment of all grades of essential hypertension, and in renovascular hypertension. It may be used alone as initial therapy or concomitantly with other antihypertensive agents, especially diuretics. RENITEC is also indicated in the treatment and prevention of heart failure. A multicenter, placebo-controlled, double-blind study of left ventricular dysfunction (SOLVD) assessed the effects of RENITEC in 6,797 patients. 2,569 patients with all degrees of symptomatic heart failure (primarily mild to moderate New York Heart Association Class II and III) were randomized into the Treatment Arm, and 4,228 patients with asymptomatic left ventricular dysfunction were randomized into the Prevention Arm. The combined results demonstrated an overall reduced risk for the development of major ischemic events. RENITEC decreased the incidence of myocardial infarction and reduced the number of hospitalizations for unstable angina pectoris in patients with left ventricular dysfunction. In addition, in the Prevention Arm, RENITEC significantly prevented the development of symptomatic heart failure and reduced the number of hospitalizations for heart failure. In the Treatment Arm, RENITEC, as an adjunct to conventional therapy, significantly reduced overall mortality and hospitalization for heart failure and improved NYHA functional class. In a similar study involving 253 patients with severe heart failure (New York Heart Association Class IV), RENITEC was shown to improve symptoms an 完全なドキュメントを読む