Ranitidine Relief

国: ニュージーランド

言語: 英語

ソース: Medsafe (Medicines Safety Authority)

有効成分:

Ranitidine hydrochloride 167.5mg equivalent to Ranitidine 150 mg

から入手可能:

Viatris Limited

INN（国際名）:

Ranitidine hydrochloride 167.5 mg (equivalent to Ranitidine 150 mg)

投薬量:

150 mg

医薬品形態:

Film coated tablet

構図:

Active: Ranitidine hydrochloride 167.5mg equivalent to Ranitidine 150 mg Excipient: Castor oil Colloidal silicon dioxide Croscarmellose sodium Hypromellose E-15 Iron oxide yellow Isopropyl alcohol Magnesium stearate Microcrystalline cellulose Purified talc   Purified water Titanium dioxide

パッケージ内のユニット:

Blister pack, Al/Al blister x 28 tablets, 28 tablets

クラス:

Pharmacy only

処方タイプ:

Pharmacy only

製:

Saraca Laboratories Limited

適応症:

Long lasting relief from acid indigestion, heartburn and symptoms resulting from excess stomach acid.

製品概要:

Package - Contents - Shelf Life: Blister pack, Al/Al blister - 20 tablets - 24 months from date of manufacture stored at or below 25°C - Blister pack, Al/Al blister - 28 tablets - 24 months from date of manufacture stored at or below 25°C

承認日:

2008-12-22

情報リーフレット

Page 1 of 3
NEW ZEALAND CONSUMER MEDICINE INFORMATION
RANITIDINE RELIEF
_RANITIDINE FILM COATED TABLETS, 150 MG AND 300 MG _
_ _
WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about RANITIDINE
RELIEF.
It does not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have risks and
benefits. Your doctor or pharmacist
has weighed the risks of you taking
RANITIDINE RELIEF against the
benefits they expect it will have for
you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE
MEDICINE. You may need to read it
again.
WHAT RANITIDINE
RELIEF IS USED FOR
RANITIDINE RELIEF is used to
provide relief from acid indigestion,
heartburn and symptoms resulting
from excess stomach acid.
RANITIDINE RELIEF contains the
active ingredient ranitidine
hydrochloride. It belongs to a group
of medicines called histamine H
2
-
antagonists. These medicines work
by reducing the amount of acid in
the stomach.
ASK YOUR DOCTOR OR PHARMACIST IF
YOU HAVE ANY QUESTIONS ABOUT
WHY THIS MEDICINE HAS BEEN
RECOMMENDED FOR YOU.
Your doctor or pharmacist may
have recommended it for another
reason.
This medicine is available from your
pharmacy in limited quantities.
This medicine is not addictive.
BEFORE YOU TAKE
RANITIDINE RELIEF
_WHEN YOU MUST NOT TAKE _
_IT _
DO NOT TAKE RANITIDINE RELIEF
IF YOU HAVE AN ALLERGY TO:
•
any medicine containing
ranitidine hydrochloride
•
any of the ingredients listed at
the end of this leaflet
_ _
Some of the symptoms of an
allergic reaction may include:
shortness of breath; wheezing or
difficulty breathing; swelling of the
face, lips, tongue or other parts of
the body; rash, itching or hives on
the skin.
DO NOT GIVE THIS MEDICINE TO A
CHILD UNDER THE AGE OF 12 YEARS.
DO NOT TAKE THIS MEDICINE AFTER
THE EXPIRY DATE PRINTED ON THE
PACK OR IF THE PACKAGING IS TORN OR
SHOWS SIGNS OF TAMPERING.
If it has expired or is damaged,
return it to your pharmacist for
disposal.
IF YOU A

製品の特徴

Page 1 of 7
NEW ZEALAND DATA SHEET
RANITIDINE RELIEF
_RANITIDINE FILM COATED TABLETS, 150 MG AND 300 MG _
NAME OF THE DRUG
Ranitidine
(as
hydrochloride).
The
chemical
name
for
ranitidine
hydrochloride
is
N-[2-[[[5-[
(dimethylamino)methyl]-2-furan-yl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine
hydrochloride. Its structural formula is:
C
13
H
22
N
4
O
3
S.HCl Molecular weight: 350.9 CAS No.: 66357-59-3
DESCRIPTION
Ranitidine hydrochloride is a white or pale yellow crystalline powder
with a slightly bitter taste and
sulfur-like odour. It is an aminoalkyl substituted furan and is
structurally different from cimetidine,
lacking the imidazole ring and the cyanoguanidine group. Ranitidine
hydrochloride is freely soluble
in water and methanol and sparingly soluble in ethanol (96%).
Ranitidine Relief tablets come in two strengths and contain either 150
mg or 300 mg of ranitidine (as
hydrochloride).
The
tablets
also
contain
the
following
excipients:
magnesium
stearate,
microcrystalline cellulose, colloidal anhydrous silica, croscarmellose
sodium, purified talc, isopropyl
alcohol, yellow iron oxide, titanium dioxide, castor oil and
hypromellose. The tablets are gluten and
lactose free.
PHARMACOLOGY
Animal experiments both _ in vitro_ and _ in vivo_ have established
that ranitidine is a selective,
competitive antagonist of histamine at H
2
-receptor sites. Ranitidine has no significant interaction at
histamine H
1
-receptors, muscarinic receptors or beta-adrenoreceptors. Ranitidine
is a potent
inhibitor of gastric secretion in the rat and dog.
All the evidence from human studies is compatible with a selective,
competitive antagonism of
histamine H
2
-receptors by ranitidine in humans. Oral or intravenous administration
of ranitidine
inhibits both basal gastric secretions and gastric acid secretion
induced by histamine, pentagastrin
and other secretagogues. On a weight basis ranitidine is between four
and nine times more potent
than cimetidine.
After oral administration of ranitidine, the plasma concentrations of
r