NORMOSOL-R- sodium chloride, sodium acetate anhydrous, sodium gluconate, potassium chloride, and magnesium chloride injection, s

国: アメリカ合衆国

言語: 英語

ソース: NLM (National Library of Medicine)

有効成分:

SODIUM CHLORIDE (UNII: 451W47IQ8X) (SODIUM CATION - UNII:LYR4M0NH37, CHLORIDE ION - UNII:Q32ZN48698), SODIUM ACETATE ANHYDROUS (UNII: NVG71ZZ7P0) (SODIUM CATION - UNII:LYR4M0NH37), SODIUM GLUCONATE (UNII: R6Q3791S76) (SODIUM CATION - UNII:LYR4M0NH37), POTASSIUM CHLORIDE (UNII: 660YQ98I10) (POTASSIUM CATION - UNII:295O53K152), MAGNESIUM CHLORIDE (UNII: 02F3473H9O) (MAGNESIUM CATION - UNII:T6V3LHY838)

から入手可能:

Hospira, Inc.

INN（国際名）:

SODIUM CHLORIDE

構図:

SODIUM CHLORIDE 526 mg in 100 mL

投与経路:

INTRAVENOUS

処方タイプ:

PRESCRIPTION DRUG

適応症:

Normosol-R pH 7.4 is indicated for replacement of acute extracellular fluid volume losses in surgery, trauma, burns or shock. Normosol-R pH 7.4 also can be used as an adjunct to restore a decrease in circulatory volume in patients with moderate blood loss. Normosol-R pH 7.4 is not intended to supplant transfusion of whole blood or packed red cells in the presence of uncontrolled hemorrhage or severe reductions of red cell volume. Normosol-R pH 7.4 is particularly valuable as a solution for use in starting blood, i.e., as a priming solution for the infusion set. No hemolysis of blood is seen at the interface or with mixed solution and blood. It may also be used as a diluent to aid in the transfusion of packed red blood cells (PRBC). Normosol-R pH 7.4 and physiologic saline solution (0.9% Sodium Chloride Injection, USP) are compatible with both young and old PRBC. None known.

製品概要:

Normosol-R pH 7.4 (Multiple Electrolytes Injection Type 1, USP) is supplied in 500 and 1000 mL single-dose flexible plastic containers (NDC 0409-7670-03 and 0409-7670-09). Exposure of pharmaceutical products to heat should be minimized. Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature.] Revised: January, 2009 Printed in USA EN-2025 Hospira, Inc., Lake Forest, IL 60045 USA  

認証ステータス:

New Drug Application

製品の特徴

NORMOSOL-R- SODIUM CHLORIDE, SODIUM ACETATE ANHYDROUS, SODIUM
GLUCONATE, POTASSIUM
CHLORIDE, AND MAGNESIUM CHLORIDE INJECTION, SOLUTION
HOSPIRA, INC.
----------
NORMOSOL -R PH 7.4
_MULTIPLE ELECTROLYTES INJECTION TYPE 1, USP_
FOR REPLACING ACUTE LOSSES OF EXTRACELLULAR FLUID
FLEXIBLE PLASTIC CONTAINER
R only
DESCRIPTION
Normosol
-R pH 7.4 is a sterile, nonpyrogenic, isotonic solution of balanced
electrolytes in water for
injection. The solution is administered by intravenous infusion for
parenteral replacement of acute
losses of extracellular fluid.
Each 100 mL of Normosol-R pH 7.4 contains sodium chloride, 526 mg;
sodium acetate, 222 mg; sodium
gluconate, 502 mg; potassium chloride, 37 mg; magnesium chloride,
hexahydrate 30 mg. May contain
hydrochloric acid and/or sodium hydroxide for pH adjustment. pH range
6.5 to 7.6; 295 mOsmol/liter
(calc.).
Electrolytes per 1000 mL (not including pH adjustment): Sodium 140
mEq; potassium 5 mEq; magnesium
3 mEq; chloride 98 mEq; acetate 27 mEq; gluconate 23 mEq.
The solution contains no bacteriostat, antimicrobial agent or added
buffer (except for pH adjustment) and
is intended only for use as a single-dose injection. When smaller
doses are required the unused portion
should be discarded.
Normosol-R pH 7.4 is a parenteral fluid and electrolyte replenisher.
Sodium Chloride, USP is chemically designated NaCl, a white
crystalline powder freely soluble in
water.
Potassium Chloride, USP is chemically designated KCl, a white granular
powder freely soluble in
water.
Magnesium Chloride, USP is chemically designated magnesium chloride,
hexahydrate (MgCl
• 6H O)
deliquescent crystals very soluble in water.
Sodium Acetate, USP is chemically designated sodium acetate, anhydrous
(C H NaO ), a hygroscopic
powder soluble in water. It has the following structural formula:
Sodium gluconate is chemically designated C H NaO , the normal sodium
salt of gluconic acid
soluble in water. It has the following structural formula:
®
x
®
2
2
2
3
2
6
11
7
Water for Injection, USP is chemically desig