MEDROL methylprednisolone tablet

国: アメリカ合衆国

言語: 英語

ソース: NLM (National Library of Medicine)

有効成分:

METHYLPREDNISOLONE (UNII: X4W7ZR7023) (METHYLPREDNISOLONE - UNII:X4W7ZR7023)

から入手可能:

REMEDYREPACK INC.

INN（国際名）:

METHYLPREDNISOLONE

構図:

METHYLPREDNISOLONE 4 mg

処方タイプ:

PRESCRIPTION DRUG

認証ステータス:

New Drug Application

製品の特徴

MEDROL- METHYLPREDNISOLONE TABLET
REMEDYREPACK INC.
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MEDROL
METHYLPREDNISOLONE
TABLETS, USP
DESCRIPTION
MEDROL Tablets contain methylprednisolone which is a glucocorticoid.
Glucocorticoids are
adrenocortical steroids, both naturally occurring and synthetic, which
are readily absorbed from the
gastrointestinal tract. Methylprednisolone occurs as a white to
practically white, odorless, crystalline
powder. It is sparingly soluble in alcohol, in dioxane, and in
methanol, slightly soluble in acetone, and in
chloroform, and very slightly soluble in ether. It is practically
insoluble in water.
The chemical name for methylprednisolone is
pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-
methyl-, (6α,11β)-and the molecular weight is 374.48. The structural
formula is represented below:
Each MEDROL Tablet for oral administration contains 2 mg, 4 mg, 8 mg,
16 mg or 32 mg of
methylprednisolone.
Inactive ingredients:
2 MG
4 MG AND 8 MG
Calcium Stearate
Calcium Stearate
Corn Starch
Corn Starch
Erythrosine Sodium
Lactose
Lactose
Sucrose
Mineral Oil
Sorbic Acid
Sucrose
16 MG AND 32 MG
Calcium Stearate
®
Corn Starch
Lactose
Mineral Oil
Sucrose
ACTIONS
Naturally occurring glucocorticoids (hydrocortisone and cortisone),
which also have salt-retaining
properties, are used as replacement therapy in adrenocortical
deficiency states. Their synthetic analogs
are primarily used for their potent anti-inflammatory effects in
disorders of many organ systems.
Glucocorticoids cause profound and varied metabolic effects. In
addition, they modify the body's
immune responses to diverse stimuli.
INDICATIONS AND USAGE
MEDROL Tablets are indicated in the following conditions:
1. ENDOCRINE DISORDERS
Primary or secondary adrenocortical insufficiency (hydrocortisone or
cortisone is the first choice;
synthetic analogs may be used in conjunction with mineralocorticoids
where applicable; in infancy
mineralocorticoid supplementation is of particular importance).
Congenital adrenal hyperplasia
Nonsuppurative thyroiditis
Hypercalcemia associat