国: ニュージーランド
言語: 英語
ソース: Medsafe (Medicines Safety Authority)
Isoflurane 100%
Multichem NZ Limited
Isoflurane 100%
Solution for inhalation
Active: Isoflurane 100%
Bottle, glass, amber x 100mL, 100 mL
Prescription
Prescription
Halocarbon Laboratories
Package - Contents - Shelf Life: Bottle, glass, amber x 100mL - 100 mL - 60 months from date of manufacture stored at or below 25°C - Bottle, glass, amber x 250mL - 250 mL - 60 months from date of manufacture stored at or below 25°C
2004-10-28
_M_-ISOFLURANE ISOFLURANE 100% USP PRESENTATION Isoflurane is a nonflammable liquid administered by vaporization. It is a general inhalation anaesthetic medicine with a mildly pungent ethereal odour containing no additives or chemical stabilizers. USES _ACTIONS _ Isoflurane is a general inhalation anaesthetic. Induction, and particularly recovery are rapid. Although slight pungency may limit the rate of induction, excessive salivation and tracheobronchial secretions are not stimulated. Pharyngeal and laryngeal reflexes are diminished quickly. Levels of anaesthesia may be changed rapidly with isoflurane. Heart rhythm remains stable. Spontaneous respiration becomes depressed as depth of anaesthesia increases and should be closely monitored and supported when necessary. During induction there is a decrease in blood pressure which returns towards normal with surgical stimulation. Blood pressure tends to fall during maintenance in direct relation to depth of anaesthesia, but cardiac rhythm remains stable. With controlled respiration and normal PaCO 2 , cardiac output tends to be maintained despite increasing depth of anaesthesia primarily through a rise in heart rate which compensates for a reduction in stroke volume. With spontaneous respiration, the resulting hypercapnia may increase heart rate and cardiac output above awake levels. Cerebral blood flow remains unchanged during light isoflurane anaesthesia but tends to rise at deeper levels. Increases in cerebrospinal fluid pressure may be prevented or reversed by hyperventilating the patient before or during anaesthesia. Electroencephalographic changes and convulsions are extremely rare with isoflurane. In general, isoflurane produces an EEG pattern similar to that seen with other volatile anaesthetics. Isoflurane appears to sensitize the myocardium to adrenaline to an 完全なドキュメントを読む