LARIAM 250 Base Milligrams Tablets

国: アイルランド

言語: 英語

ソース: HPRA (Health Products Regulatory Authority)

有効成分:

MEFLOQUINE HYDROCHLORIDE

から入手可能:

Roche Products Limited

INN（国際名）:

MEFLOQUINE HYDROCHLORIDE

投薬量:

250 Base Milligrams

医薬品形態:

Tablets

処方タイプ:

Product subject to prescription which may be renewed (B)

認証ステータス:

Authorised

承認日:

0000-00-00

情報リーフレット

-1- 

Lariam-PIL-IE-1306-250-Tab 
PATIENT INFORMATION LEAFLET      

IRELAND 

LARIAM
®
 250 MG 
ROCHE 
TABLETS 

Mefloquine 

PLEASE READ THIS LEAFLET CAREFULLY BEFORE YOU START TO TAKE YOUR
MEDICINE.  IF YOU HAVE ANY 
QUESTIONS OR ARE NOT SURE ABOUT ANYTHING,
ASK YOUR DOCTOR OR PHARMACIST. 

In this leaflet you will find: 

1. What is Lariam? 
2. Things you should know before taking Lariam 
3. How to take this medicine 
4. Possible side effects 
5. Storing your medicine 
6. Other information 

1. WHAT IS LARIAM?  

This medicine is used to treat malaria and to help prevent you from
catching malaria. 

Malaria is a life threatening disease and a major health risk
for travellers visiting tropical 
countries.   

It occurs when small parasites are passed from one person to
another by the bites of certain 
mosquitoes.  Lariam is especially useful if you are travelling to
countries where there is a type 
of malaria which is particularly difficult to treat.  No single
medicine is effective against all 
malaria parasites.  The choice of a particular
medicine depends on the sensitivity of the 
malaria parasites found in the area to be visited.  Your doctor
will advise you whether Lariam 
is suitable for the area to which you wish to go.  

TO HELP MINIMISE YOUR CHANCE OF CATCHING THE DISEASE AND TO
PROTECT YOU FROM POSSIBLE 
SERIOUS SIDE EFFECTS IT IS IMPORTANT THAT YOU READ THIS
LEAFLET CAREFULLY.  ASK YOUR DOCTOR TO 
EXPLAIN ANYTHING YOU DO NOT UNDERSTAND. 

2. THINGS YOU SHOULD KNOW BEFORE TAKING LARIAM 

DO NOT TAKE LARIAM IF YOU HAVE, OR HAVE EVER HAD: 


  depression, thoughts about suicide and
self-endangering behaviour 

  any other mental problem, including anxiety disorder,
schizophrenia or psychosis (losing 
touch with reality) 

  fits (seizures or convulsions) 

  an allergy to quinin

製品の特徴

SUMMARY OF PRODUCT CHARACTERISTICS
1 NAME OF THE MEDICINAL PRODUCT
Lariam 250 mg Tablets
2 QUALITATIVE AND QUANTITATIVE COMPOSITION
Each tablet contains 250 mg mefloquine (as 274.09 mg mefloquine hydrochloride).
Each tablet contains 50.61 mg of lactose monohydrate
For a full list of excipients see section 6.1.
3 PHARMACEUTICAL FORM
Tablets
White to off-white cylindrical biplanar tablets, cross-scored and imprinted Roche on one face.
The tablet can be divided into equal halves to facilitate dosing.
4 CLINICAL PARTICULARS
4.1 THERAPEUTIC INDICATIONS
Therapy and prophylaxis of malaria.
_Therapy_: Lariam is especially indicated for therapy of _P. falciparum _malaria in which the pathogen has become
resistant to other antimalarial agents.
Following treatment of _P. vivax _malaria with Lariam, relapse prophylaxis with an 8-amino-quinoline derivative, for
example primaquine, should be considered in order to eliminate parasites in the hepatic phase.
_Prophylaxis_: Malaria prophylaxis with Lariam is particularly recommended for travellers to malarious areas in which
multiple resistant _P. falciparum _strains occur.
4.2 POSOLOGY AND METHOD OF ADMINISTRATION
When chemoprophylaxis with Lariam fails, physicians should carefully evaluate which antimalarial to use for therapy.
Regarding the use of halofantrine, see sections 4.3, 4.4 and 4.5.
_CHEMOPROPHYLAXIS_
In order to ensure, before arrival in endemic area, that Lariam administration is well tolerated, it is recommended to start
chemoprophylaxis with Lariam 10 days before departure (i.e. first intake 10 days before departure and 2
nd
intake 3 days
before departure). Subsequent doses should be taken once a week (at a fixed day).
IRISH MEDICINES BOARD
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