国: ニュージーランド
言語: 英語
ソース: Medsafe (Medicines Safety Authority)
Fluocortolone pivalate 0.1%{relative}; Lidocaine hydrochloride 2%{relative}
LEO Pharma Limited
Fluocortolone pivalate 0.1% w/w
1mg/20mg
Rectal cream
Active: Fluocortolone pivalate 0.1%{relative} Lidocaine hydrochloride 2%{relative} Excipient: Benzyl alcohol Cetostearyl alcohol Dibasic sodium phosphate dodecahydrate Liquid paraffin Monobasic sodium phosphate dihydrate Polysorbate 60 Purified water Sodium edetate Sorbitan stearate White soft paraffin
Tube, aluminium, epoxy resin coated with polyethylene screw cap and polypropylene nozzle, 30 g
Prescription
Prescription
Bayer AG
Package - Contents - Shelf Life: Tube, aluminium, epoxy resin coated with polyethylene screw cap and polypropylene nozzle - 30 g - 3 years from date of manufacture stored at or below 30°C
2004-11-16
DOLOPROCT ® RECTAL CREAM OR SUPPOSITORY _(DOLL-O-PROKT) _ _Rectal cream: 1mg/g fluocortolone pivalate and 20mg/g lidocaine hydrochloride _ _Suppository: 1mg fluocortolone pivalate and 40mg lidocaine hydrochloride(each) _ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET? This leaflet answers some common questions about DOLOPROCT ® . It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of your taking DOLOPROCT ® against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT DOLOPROCT ® IS USED FOR DOLOPROCT ® RECTAL CREAM AND DOLOPROCT ® SUPPOSITORIES are used for the relief of pain, swelling, burning and itching in the lower part of the rectum (back passage) and around the anus, which can be caused by haemorrhoids (also known as piles). DOLOPROCT ® rectal cream is also used to treat anal eczema, a skin rash around the anal area that can be very red, swollen and itchy. DOLOPROCT ® rectal cream and suppositories both contain an anti-inflammatory medicine called FLUOCORTOLONE PIVALATE _(PRONOUNCED FLU-COR-TOE-LONE PIV-A-LATE)_ to reduce swelling, burning and itching as well as a local anesthetic called LIDOCAINE HYDROCHLORIDE _(PRONOUNCED LIE-DOE-CANE HI-DRO-CHLOR-IDE)_ to reduce pain. DOLOPROCT ® can help to reduce pain, swelling, burning and itching in the rectum and anal area. However, it will not eliminate the CAUSE of these symptoms. Speak to your doctor or pharmacist if you have any further questions. Your doctor may have prescribed DOLOPROCT ® for a 完全なドキュメントを読む
DOLOPROCT ® RECTAL CREAM OR SUPPOSITORIES CONTAINING FLUOCORTOLONE PIVALATE AND LIDOCAINE HYDROCHLORIDE PRESENTATION 1 g of white, opaque rectal cream contains 1 mg fluocortolone pivalate and 20 mg lidocaine hydrochloride (anhydrous). 1 yellowish-white suppository contains 1 mg fluocortolone pivalate and 40 mg lidocaine hydrochloride (anhydrous). USES _ACTIONS _ Fluocortolone exerts an anti-inflammatory, antiallergenic and antipruritic effect. Capillary dilatation, intercellular edema and tissue infiltration regress; capillary proliferation is suppressed. _PHARMACODYNAMIC PROPERTIES _ Pharmacotherapeutic group: topical antihemorrhoidal agent ATC code: C05 AX 03 Fluocortolone pivalate Fluocortolone pivalate inhibits inflammatory and allergic skin reactions, and alleviates subjective symptoms, such as pruritus, smarting, and pain. The substance reduces dilatation of the capillaries, edema of the interstitial cells and infiltration of the tissues. Capillary multiplication is inhibited . Lidocaine hydrochloride Lidocaine hydrochloride is a standard local anesthetic which has been in use for many years. As it has analgesic and antipruritic effects, it has been found to be effective when used in suppositories and creams designed for the treatment of hemorrhoidal complaints. The suppression of pain and pruritus is the result of the inhibition of afferent nervous pathways. _PHARMACOKINETIC PROPERTIES _ The DOLOPROCT rectal cream/suppositories are topical preparations which display their anti-inflammatory and analgesic effects at the site of application. The active ingredients diffuse out of the preparations into the inflamed tissue, are partially absorbed, distributed by the circulatory system, metabolised and finally excreted. In order to obtain a local therapeutic effect, pharmacologically effective plasma levels are not required. In order to assess the risk of systemic effects after rectal application of the D 完全なドキュメントを読む