国: アメリカ合衆国
言語: 英語
ソース: NLM (National Library of Medicine)
DEXAMETHASONE (UNII: 7S5I7G3JQL) (DEXAMETHASONE - UNII:7S5I7G3JQL)
Vedco, Inc
PRESCRIPTION
INDICATIONS: Dexamethasone Solution is indicated for the treatment of primary bovine ketosis and as an anti-inflammatory agent in the bovine and equine. As supportive therapy, Dexamethasone Solution may be used in the management of various rheumatic, allergic, dermatologic, and other diseases known to be responsive to anti-inflammatory corticosteroids. Dexamethasone Solution may be used intravenously as supportive therapy when an immediate hormonal response is required. Bovine Ketosis Dexamethasone Solution is offered for the treatment of primary ketosis. The gluconeogenic effects of dexamethasone, when administered intramuscularly, are generally noted within the first six to twelve hours. When Dexamethasone Solution is used intravenously, the effects may be noted sooner. Blood sugar levels rise to normal levels rapidly and generally rise to above normal levels within 12 to 24 hours. Acetone bodies are reduced to normal concentrations usually within 24 hours. The physical attitude of animals t
HOW SUPPLIED: Dexamethasone Solution, 2 mg/mL, 100 mL multiple dose vial. Store between 20° - 25°C (68° - 77° F) . Manufactured by: Med-Pharmex, Inc. Pomona, CA 91767-1861 Rev 4/14 VINV-DEX2-100M
Abbreviated New Animal Drug Application
DEXAMETHASONE- DEXAMETHASONE SOLUTION INJECTION, SOLUTION VEDCO, INC ---------- DEXAMETHASONE SOLUTION NDC 50989-074-12 DEXAMETHASONE SOLUTION 2 mg/mL Sterile Multiple Dose Vial NET CONTENTS: 100ML VEDCO For Intravenous or Intramuscular Injection Veterinary For Animal Use Only KEEP OUT OF REACH OF CHILDREN ANADA# 200-456, Approved by FDA CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Distributed BY VEDCO, INC St. Joseph, MO 64507 TAKE TIME OBSERVE LABEL DIRECTIONS DESCRIPTION: Dexamethasone is a synthetic analogue of prenisolone, having similar but more potent anti-inflammatory therapeutic action and diversified hormonal and metabolic effects. Modification of the basic corticoid structure as achieved in Dexamethasone Solution offers enhanced anti-inflammatory effect compared to older corticosteroids. The dosage of Dexamethasone Solution required is markedly lower than that of prednisone and prednisolone. Dexamethasone Solution is not species-specific; however, the veterinarian should read the sections on INDICATIONS, DOSAGE, SIDE EFFECTS, CONTRAINDICATIONS, PRECAUTIONS, and WARNINGS before this drug is used. Dexamethasone Solution is intended for _intravenous_ or _intramuscular _ administration. Each mL contains 2 mg dexamethasone, 500 mg polyethylene glycol 400, 9 mg benzyl alcohol, 1.8 mg methylparaben and 0.2 mg propylparaben as preservatives, 4.75% alcohol, HCl and/or sodium hydroxide to adjust pH to approximately 4.9, Water for Injection q.s. EXPERIMENTAL STUDIES: Experimental animal studies on dexamethasone have revealed that it possesses greater anti-inflammatory activity than many steroids. Veterinary clinical evidence indicates dexamethasone has approximately twenty times the anti-inflammatory activity of prednisolone and 70 to 80 times that of hydrocortisone. Thymus involution studies show dexamethasone possesses 25 times the activity of prednisolone. In reference to mineralocorticoid activity, dexamethasone does not cause significant sodium or water reten 完全なドキュメントを読む