Apo-Hydrochlorothiazide 50mg Tablet

国: マレーシア

言語: 英語

ソース: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

有効成分:

HYDROCHLOROTHIAZIDE

から入手可能:

PHARMAFORTE (MALAYSIA) SDN. BHD.

INN（国際名）:

HYDROCHLOROTHIAZIDE

パッケージ内のユニット:

30 Tablet Tablets

製:

APOTEX INC. - ETOBICOKE SITE

情報リーフレット

APO-HYDROCHLOROTHIAZIDE TABLET
_CONSUMER MEDICATION INFORMATION LEAFLET_
Hydrochlorothiazide (25mg,50mg)
1
WHAT IS IN THIS LEAFLET
1.
What Apo-Hydrochlorothiazide is
used for
2.
How
Apo-Hydrochlorothiazide
works
3.
Before
you
use
Apo-
Hydrochlorothiazide
4.
How
to
use
Apo-
Hydrochlorothiazide
5.
While you are using it
6.
Side effects
7.
Storage
and
Disposal
of
Apo-
Hydrochlorothiazide
8.
Product Description
9.
Manufacturer
and
Product
Registration
Holder
10.
Date of revision
WHAT
APO-HYDROCHLOROTHIAZIDE
IS
USED FOR
Hydrochlorothiazide treats fluid retention
(edema) in people with congestive heart
failure, cirrhosis of the liver, or kidney
disorders,
or
edema
caused
by
taking
steroids or estrogen.
This medication is also used to treat high
blood pressure (hypertension).
HOW APO-HYDROCHLOROTHIAZIDE WORKS
Hydrochlorothiazide is a thiazide diuretic
(water pill) that helps prevent your body
from reabsorbing too much salt in the
kidney, which can cause fluid retention.
BEFORE
YOU
USE
APO-
HYDROCHLOROTHIAZIDE
-
_When you must not use it _
Do
not
use
this
product
if
you
are
allergic to hydrochlorothiazide, or any
ingredients in this medication.
_Pregnancy and lactation _
Do
not
take
Apo-
Hydrochlorothiazide
if
you
are
pregnant, trying to get pregnant or
think you may be pregnant.
Do
not
take
Apo-
Hydrochlorothiazide
if
you
are
breast-feeding. Ask your doctor or
pharmacist for advice before taking
any medicine.
_ _
_ _
-
_Before you start to use it _
Before
you
start
to
use
Apo-
Hydrochlorothiazide,
your
doctor
should
know
if
you
have any
other
medical
conditions,
for
example
impaired
liver
function,
electrolyte
imbalance and gout.
You should also let your doctor know if
you
have
any
history
of
allergy
or
bronchial asthma.
-
_Taking other medicines _
_ _
Some
medications
might
cause
complications when taken together with
Apo-Hydrochlorothiazide.
These
medications
include
steroid
or
adrenocorticotropic
hormone
[ACTH]
(hypokalaemia/
low potassium
levels),
thiazides, insulins (requiring a change of
dose),
diuretics (increase

製品の特徴

APO-HYDROCHLOROTHIAZIDE
HYDROCHLOROTHIAZIDE TABLETS USP 25MG AND 50MG
DIURETIC ANTIHYPERTENSIVE
PHARMACOLOGY
:
Hydrochlorothiazide inhibits reabsorption of sodium and chloride in
the distal tubule thus promoting water
loss. The higher urine volume increases potassium loss, therefore
restricting salt intake decreases
potassium loss. Oral doses are well absorbed and reach peak effect in
about 4 hours, with a 6 to 12 hours
duration. It is excreted unchanged in the urine with a half-life of 3
to 5 hours. The mild blood pressure
reducing effects are initially due to volume reduction but the
persisting effect includes other undetermined
mechanisms that reduce peripheral resistance. A high salt intake
reverse its antihypertensive effect.
INDICATIONS
:
Adjunctive therapy in edema associated with congestive heart failure,
hepatic cirrhosis, corticosteroid and
estrogen therapy and in edema of renal origin (i.e. nephrotic
syndrome, acute glomerulonephritis, chronic
renal disease). In the management of hypertension, hydrochlorothiazide
may be used alone or as an
adjunct to other antihypertensive drugs. Since it enhances the action
of these agents, their dosage must be
reduced to avoid an excessive drop in blood pressure and other adverse
effects.
CONTRAINDICATIONS
:
Anuria; discontinue if increasing azotemia and oliguria occur during
treatment of severe progressive renal
disease. Do not use in patients known to be sensitive to thiazides or
other sulfonamide derived drugs.
PRECAUTIONS
:
May precipitate or increase azotemia; cumulative effects may develop
in presence of impaired renal
function; discontinue if increasing azotemia and oliguria occur during
treatment of severe progressive renal
disease. Use with caution in impaired hepatic function or progressive
liver disease since minor alterations
of fluid and electrolyte balance or of serum ammonia may precipitate
hepatic coma. The possibility of
sensitivity reaction should be considered in patients with or without
a history of allergy or bronchial
asthma. The possibility of