Anprodryl Syrup

国: マレーシア

言語: 英語

ソース: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

有効成分:

DIPHENHYDRAMINE HYDROCHLORIDE; AMMONIUM CHLORIDE.

から入手可能:

MALAYSIAN PHARMACEUTICAL INDUSTRIES SDN. BHD.

INN（国際名）:

DIPHENHYDRAMINE HYDROCHLORIDE; AMMONIUM CHLORIDE.

パッケージ内のユニット:

60ml mL; 100ml mL

製:

MALAYSIAN PHARMACEUTICAL INDUSTRIES SDN. BHD.

情報リーフレット

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
1
ANPRODRYL SYRUP
Diphenhydramine Hydrochloride/Ammonium Chloride (12.5mg/125mg per 5ml)
WHAT IS IN THIS LEAFLET:
1.
What Anprodryl Syrup is used
for
2.
How Anprodryl Syrup works
3.
Before
you
use
Anprodryl
Syrup
4.
How to use Anprodryl Syrup
5.
While you are using it
6.
Side effects
7.
Storage
and
disposal
of
Anprodryl Syrup
8.
Product Description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of Revision
WHAT
ANPRODRYL
SYRUP
IS
USED
FOR
It
is
indicated
for
the
control
of
cough,
nasal
(nose)
congestion,
sneezing,
lachrymation
(flow
of
tears) and airway congestion due to
common
cold
and
allergic
conditions.
HOW ANPRODRYL SYRUP WORKS
Diphenhydramine
hydrochloride
belongs
to
group
of
medicines
called
antihistamine.
It
works
by
blocking
the
effects
of
a
natural
compound in the body, known as
histamine,
that
is
released
during
allergic
reactions.
Ammonium
chloride
encourages
productive
cough by increasing the volume of
airway secretion.
BEFORE YOU USE ANPRODRYL SYRUP
-
_When you must not use it _

If
you
are
allergic
(hypersensitive)
to
diphenhydramine
hydrochloride
and
other
similar antihistamines.

If
you
are
a
nursing
mother.

To premature infants, full
term babies.
-
_Before you start to use it _
You must tell your doctor if:

You have allergies to any
medicine which you have
taken
previously
to
treat
your current condition.

You are pregnant, trying to
become pregnant or breast-
feeding.
Should be used with caution in
people with conditions such as:

Angle-closure glaucoma –
a sudden, painful condition
in the eye as well as blurry
vision caused by increased
pressure
that
is
due
to
blockage of a watery fluid.

Liver disease

Hyperthyroidism
–
a
condition
in
which
the
thyroid gland is overactive
and
makes
excessive
amounts
of
thyroid
hormone.

Heart
and
blood
vessel
disease

High blood pressure

Urinary retention

Prostatic
hyperplasia
-
benign enlargement of the
prostate.

Pyloroduodenal
obstruction
–
related

製品の特徴

7170-02
ANPRODRYL SYRUP
NAME AND STRENGTH OF ACTIVE SUBSTANCE:
Each 5ml syrup contains:
Diphenhydramine Hydrochloride ……………………
……………12.5mg
Ammonium
Chloride……………………………………………… 125mg
PRODUCT DESCRIPTION:
A caramel colour liquid with Prune flavour and sweet taste.
PHARMACODYNAMICS
:
Diphenhydramine hydrochloride is a monoethanolamine-derivative
antihistamine
with sedative and antihistamine
properties. It also has anti-emetic, anticholinergic and local
anaesthethic properties. Antihistamines compete with
histamine for cell receptor sites on effector cells. Ammonium chloride
encourages productive cough by increasing the
volume of bronchial secretion.
PHARMACOKINETICS:
Diphenhydramine hydrochloride is well absorbed from the
gastrointestinal tract, although high first-pass metabolism
appears to affect systemic availability. Peak plasma concentrations
are achieved about 1 to 4 hours after administration
by mouth. Diphenhydramine is widely distributed throughout the body
including the central nervous system. It crosses
the placenta and has been detected in breast milk. It is highly bound
to plasma proteins. Diphenhydramine is extensively
metabolised and is excreted mainly in the urine as metabolites and
little is excreted as unchanged drug. The elimination
half-life has been reported to range from 2.4 to 9.3 hours. Ammonium
chloride is absorbed from the gastrointestinal
tract. It is converted to urea by the liver via the ornithine cycle.
Its metabolism releases hydrogen ions and bicarbonate,
which decreases the pH of the urine and promotes diuresis. Ammonium
chloride is excreted renally.
INDICATION:
For the control of cough, nasal congestion, sneezing, lachrymation and
bronchial congestion due to common cold and
allergic conditions.
_Should not be used in children less than 2 years of age. _
RECOMMENDED DOSAGE:
Adults : One to two teaspoonfuls (5-10ml), three to four times daily.
Children (2-12 years) : 2.5-5ml three or four times daily or 5mg per
kg body –we