国: アメリカ合衆国
言語: 英語
ソース: NLM (National Library of Medicine)
AMPICILLIN SODIUM (UNII: JFN36L5S8K) (AMPICILLIN - UNII:7C782967RD)
Hospira, Inc
AMPICILLIN SODIUM
AMPICILLIN 100 mg in 1 mL
PRESCRIPTION DRUG
Abbreviated New Drug Application
AMPICILLIN AND SULBACTAM- AMPICILLIN AND SULBACTAM INJECTION, POWDER, FOR SOLUTION HOSPIRA, INC ---------- AMPICILLIN AND SULBACTAM FOR INJECTION, USP PHARMACY BULK PACKAGE NOT FOR DIRECT INFUSION TO REDUCE THE DEVELOPMENT OF DRUG-RESISTANT BACTERIA AND MAINTAIN THE EFFECTIVENESS OF AMPICILLIN AND SULBACTAM FOR INJECTION AND OTHER ANTIBACTERIAL DRUGS, AMPICILLIN AND SULBACTAM FOR INJECTION SHOULD BE USED ONLY TO TREAT INFECTIONS THAT ARE PROVEN OR STRONGLY SUSPECTED TO BE CAUSED BY BACTERIA. DESCRIPTION Ampicillin and Sulbactam for Injection, USP is a sterile injectable antibacterial combination consisting of the semisynthetic antibacterial ampicillin sodium and the beta-lactamase inhibitor sulbactam sodium for parenteral administration. THE INTENT OF THIS PHARMACY BULK PACKAGE IS FOR PREPARATION OF SOLUTIONS FOR IV INFUSION ONLY. Ampicillin sodium is derived from the penicillin nucleus, 6-aminopenicillanic acid. Chemically, it is monosodium (2S, 5R, 6R)-6-[(R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1- azabicyclo[3.2.0]heptane-2-carboxylate and has a molecular weight of 371.39. Its chemical formula is C H N NaO S. The structural formula is: Sulbactam sodium is a derivative of the basic penicillin nucleus. Chemically, sulbactam sodium is sodium penicillinate sulfone; sodium (2S, 5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylate 4,4-dioxide. Its chemical formula is C H NNaO S with a molecular weight of 255.22. The structural formula is: Ampicillin and Sulbactam for Injection, USP parenteral combination, is available as a white to yellowish dry powder for reconstitution. Ampicillin and Sulbactam for Injection, USP dry powder is freely soluble in aqueous diluents to yield pale yellow to yellow solutions containing ampicillin sodium and sulbactam sodium equivalent to 250 mg ampicillin per mL and 125 mg sulbactam per mL. The pH of the solutions is between 8 and 10. 16 18 3 4 8 10 5 Dilute solutions (up to 30 mg ampicillin and 15 mg sulbactam per mL) are essentially colorless to pale 完全なドキュメントを読む