国: ニュージーランド
言語: 英語
ソース: Medsafe (Medicines Safety Authority)
Amitriptyline hydrochloride 25mg; ; Amitriptyline hydrochloride 25mg
AFT Pharmaceuticals Ltd
Amitriptyline hydrochloride 25 mg
25 mg
Film coated tablet
Active: Amitriptyline hydrochloride 25mg Excipient: Colloidal silicon dioxide Hypromellose Lactose Macrogol 400 Magnesium stearate Maize starch Microcrystalline cellulose Povidone Purified talc Quinoline yellow Sodium starch glycolate Titanium dioxide Active: Amitriptyline hydrochloride 25mg Excipient: Colloidal silicon dioxide Hypromellose Lactose Macrogol 400 Magnesium stearate Maize starch Microcrystalline cellulose Povidone Purified talc Quinoline yellow Sodium starch glycolate Titanium dioxide
Blister pack, PVC/Al, 50 tablets, 50 tablets
Prescription
Prescription
R.L. Fine Chem
Package - Contents - Shelf Life: Blister pack, PVC/PE/PVDC - 50 tablets - 5 years from date of manufacture stored at or below 25°C
2008-04-01
NEW ZEALAND DATA SHEET Page 1 of 11 1 AMIROL Amitriptyline hydrochloride 2 QUALITATIVE AND QUANTITATIVE COMPOSITION Amirol 10 - Film coated tablets 10mg Amirol 25 - Film coated tablets 25mg 3 PHARMACEUTICAL FORM Film coated tablets AMIROL 10mg tablets are blue, film coated biconvex tablets, 9/32" diameter. Each tablet contains 10mg amitriptyline hydrochloride. AMIROL 25mg tablets are yellow, film coated biconvex tablets, 9/32" diameter. Each tablet contains 25mg amitriptyline hydrochloride. For both strengths do not halve tablet, dose equivalent when the tablet is divided has not been established. 4 CLINICAL PARTICULARS 4.1 Therapeutic indications AMIROL is recommended for the treatment of depression. 4.2 Dose and method of administration DEPRESSION DOSAGE CONSIDERATIONS Dosage should be initiated at a low level and increased gradually, noting carefully the clinical response and any evidence of intolerance. Oral Dosage. Do not halve tablet, dose equivalent when the tablet is divided has not been established. INITIAL ADULT DOSAGE FOR OUTPATIENTS 75mg of amitriptyline a day in divided doses is usually satisfactory. If necessary, this may be increased to a total of 150mg a day. Increases are made preferably in the late afternoon and/or bedtime doses. The sedative effect is usually rapidly apparent. The antidepressant activity may be evident within 3 or 4 days or may take up to 30 days to develop adequately. Alternate methods of initiating therapy in outpatients are to begin therapy with 50 to 100mg amitriptyline preferably in the evening or at bedtime; this may be increased by 25 to 50mg as necessary to a total of 150mg per day. Initiate therapy with one 75mg capsule or tablet preferably in the evening or at bedtime and increase, if necessary, to two, or one in the morning and one in the evening. NEW ZEALAND DATA SHEET Page 2 of 11 DOSAGE FOR HOSPITALISED PATIENTS 100mg a day may be required initially. This can be increased gradually to 200mg a day if necessary. A small number of hospitalised patients may need as mu 完全なドキュメントを読む