国: イギリス
言語: 英語
ソース: MHRA (Medicines & Healthcare Products Regulatory Agency)
Allopurinol
DE Pharmaceuticals
M04AA01
Allopurinol
300mg
Oral tablet
Oral
No Controlled Drug Status
Valid as a prescribable product
BNF: 10010400
1 PACKAGE LEAFLET: INFORMATION FOR THE USER ALLOPURINOL 100MG AND 300MG TABLETS (Allopurinol) READ ALL OF THIS LEAFLET CAREFULLY BEFORE YOU START TAKING THIS MEDICINE BECAUSE IT CONTAINS IMPORTANT INFORMATION FOR YOU. • Keep this leaflet. You may need to read it again. • If you have any further questions, ask your doctor or pharmacist. • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours. • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4. WHAT IS IN THIS LEAFLET : 1. What Allopurinol Tablets are and what are they used for 2. What you need to know before you take Allopurinol Tablets 3. How to take Allopurinol Tablets 4. Possible side effects 5. How to store Allopurinol Tablets 6. Contents of the pack and other information 1. WHAT ALLOPURINOL TABLETS ARE AND WHAT ARE THEY USED FOR Allopurinol belongs to a group of medicines called enzyme inhibitors. These medicines inhibit the amount of uric acid production in your body. Allopurinol works by slowing down the speed of certain chemical reactions in your body to lower the level of uric acid in the blood and urine. Allopurinol Tablets are used to treat the following conditions: Gout (increased uric acid quantity in the body). The uric acid builds up in your joints and tendons as crystals causing an inflammatory reaction. The inflammation causes the skin around certain joints to become swollen, tender and sore when only slightly touched. You may also get severe pain when the joint is moved. Kidney stones formation and certain other types of kidney diseases due to increase in the amount of uric acid in the body Some types of Cancer due to increase in the amount of uric acid in the body Enzyme disorders due to increase in the amount of uric acid in the body 2. WHAT YOU NEED TO KNOW BEFORE YOU TAKE ALLOPURINOL TABLETS DO NOT TAKE ALLOPURINOL TABLETS: if you are 完全なドキュメントを読む
1. NAME OF THE MEDICINAL PRODUCT Allopurinol 300 mg Tablets 2 QUALITATIVE AND QUANTITATIVE COMPOSITION Each tablet contains Allopurinol 300mg Excipients with known effect: Each 300 mg tablets contains 149.6 mg of lactose monohydrate Each 300mg tablet contains 2.6mg of Sunset Yellow FCF. For the full list of excipients, see section 6.1. 3 PHARMACEUTICAL FORM Tablet 300mg: Peach colored, approx 11mm round, biconvex, uncoated tablets with 'AL' & '300' separated by breakline on one side & plain on other side. The score line is only to facilitate breaking for ease of swallowing and not to divide the tablet into equal doses. 4 CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS Allopurinol is indicated for reducing urate/uric acid formation in conditions where urate/uric acid deposition has already occurred (e.g. gouty arthritis, skin tophi, nephrolithiasis) or is a predictable clinical risk (e.g. treatment of malignancy potentially leading to acute uric acid nephropathy). The main clinical conditions where urate/uric acid deposition may occur are: idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate levels occur either spontaneously, or after cytotoxic therapy; certain enzyme disorders which lead to overproduction of urate, for example: hypoxanthine-guanine phosphoribosyltransferase, including Lesch-Nyhan syndrome; glucose-6-phosphatase including glycogen storage disease; phosphoribosylpyrophosphate synthetase, phosphoribosylpyrophosphate amidotransferase; adenine phosphoribosyltransferase. Allopurinol is indicated for management of 2,8-dihydroxyadenine (2,8-DHA) renal stones related to deficient activity of adenine phosphoribosyltransferase. Allopurinol is indicated for the management of recurrent mixed calcium oxalate renal stones in the presence of hyperuricosuria, when fluid, dietary and similar measures have failed. 4.2 POSOLOGY AND METHOD OF ADMINISTRATION Posology Adults Allopurinol should be introduc 完全なドキュメントを読む