Acesin 62.5% ww Water Soluble Powder

国: マレーシア

言語: 英語

ソース: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

有効成分:

Tylvalosin Tartrate

から入手可能:

Nam Pharma Sdn. Bhd.

INN（国際名）:

Tylvalosin Tartrate

パッケージ内のユニット:

100 gm; 400 gm

製:

Nam Pharma Sdn. Bhd.

製品の特徴

ACESIN 62.5% W/W WATER SOLUBLE POWDER
ACESIN 62.5% W/W WATER SOLUBLE POWDER appears to be an almost white
color
powder.
COMPOSITION:
Each g contains:
Tylvalosin (as tylvalosin tartrate) 625 mg
PHARMACODYNAMICS:
Tylvalosin
is
a
macrolide
antibiotic.
Macrolides
are
metabolites
or
derivatives
of
metabolites of soil organisms obtained by fermentation. They interfere
with protein
synthesis by reversibly binding to the 50S ribosome subunit. They are
generally
considered bacteriostatic.
Tylvalosin has activity against pathogenic organisms isolated from a
range of animal
species-mainly
Gram-positive
organisms
and
mycoplasma
(e.g.
Mycoplasma
gallisepticum)
but
also
some
Gram-negative
organisms,
including
Lawsonia
intracellularis and Ornithobacterium rhinotracheale.
Bacteria
can
develop
resistance
to
antimicrobial
substances.
There
are
multiple
mechanisms responsible for resistance development to macrolide
compounds.
Cross-resistance within the macrolide group of antibiotics cannot be
excluded.
PHARMACOKINETICS:
Tylvalosin
tartrate
is
rapidly
absorbed
after
oral
administration
of
the
veterinary
medicinal
product.
Tylvalosin
is
widely
distributed
in
tissues
with
the
highest
concentrations found in the respiratory tissues, bile, intestinal
mucosa, spleen, kidney
and liver. Tylvalosin has been shown to concentrate in phagocytic
cells and gut
epithelial cells. The major metabolite of tylvalosin is
3-acetyltylosin (3-AT), which is also
microbiologically active.
INDICATIONS:
Pigs:
Treatment and metaphylaxis of porcine proliferative enteropathy
(ileitis) caused by
_Lawsonia intracellularis_.
The presence of the disease in the herd should be established before
metaphylaxis.
Chickens
Treatment
and
metaphylaxis
of
respiratory
infections
caused
by
_Mycoplasma _
_gallisepticum_
in
chickens.
The
presence
of
the
disease
in
the
flock
should
be
established before metaphylactic treatment. As an aid in reducing the
development of
clinical signs and mortality from respiratory disease in flocks, where
infection in ovum
with _ Mycoplasma galli