Nazione: Malesia
Lingua: inglese
Fonte: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
PANTOPRAZOLE SODIUM SESQUIHYDRATE
Duopharma Marketing Sdn. Bhd.
PANTOPRAZOLE SODIUM SESQUIHYDRATE
50x10 Tablets; 10x10 Tablets; 9x10 Tablets; 6x10 Tablets; 1x10 Tablets; 3x10 Tablets
Hetero Labs Limited
Consumer Medication Information Leaflet (RiMUP) 1 PANOSEC TABLET 20MG Pantoprazole Sodium Sesquihydrate WHAT IS IN THIS LEAFLET 1. What Panosec Tablet 20mg is used for 2. How Panosec Tablet 20mg works 3. Before you use Panosec Tablet 20mg 4. How to take Panosec Tablet 20mg 5. While you are using Panosec Tablet 20mg 6. Side Effects 7. Storage and Disposal of Panosec Tablet 20mg 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of Revision 1. WHAT PANOSEC TABLET 20MG IS USED FOR Panosec Tablet 20mg is used: • To treat symptoms (e.g. heartburn, acid regurgitation, pain on swallowing) associated with mild reflux disease caused by reflux of acid from the stomach. • For the long-term management and prevention of reflux oesophagitis from coming back. • For the prevention of stomach and duodenal ulcers caused by non- steroidal anti- inflammatory drugs (NSAIDs), in people at risk who need to take NSAIDs continuously. 2. HOW PANOSEC TABLET 20MG WORKS Panosec Tablet 20mg is a selective “proton pump inhibitor”, a medicine which reduces the amount of acid produced in your stomach 3. BEFORE YOU USE PANOSEC TABLET 20MG _When you must not take it _ Do not take Panosec Tablet 20mg: • if you are allergic (hypersensitive) to pantoprazole or any of the other ingredients of Panosec Tablet 20mg . • if you are allergic to medicines containing other proton pump inhibitors. • Tell your doctor before taking this medicine, if you are due to have a specific blood test (Chromogranin A) _Before you start to take it_ Take special care with Panosec Tablet 20mg • If you have severe liver problems. Please tell your doctor if you have ever had problems with your liver. Doctor will check your liver enzymes more frequently, especially when you are taking Panosec Tablet 20mg as a long- term treatment. • If you need to take medicines called NSAIDs continuously with prescribed Panosec Tablet 20mg. you might have an increased risk of developing stomach and intestinal complication. • If you have reduced Leggi il documento completo
PANOSEC TABLET 20MG NAME OF PRODUCT Pantoprazole Gastro-Resistance Tablet 20mg NAME AND STRENGTH OF ACTIVE INGREDIENT NAME : Pantoprazole Sodium Sesquihydrate STRENGTH : 20mg ROUTE OF ADMINISTRATION: ORAL PRODUCT DESCRIPTION Yellow to pale yellow, oval, biconvex gastro resistant tablets imprinted‘H125’ on one side with black ink and plain on the other side. PHARMACODYNAMICS MECHANISM OF ACTION Pantoprazole is a substituted benzimidazole which inhibits the secretion of hydrochloric acid in the stomach by specific blockade of the proton pumps of the parietal cells. Pantoprazole is converted to its active form in the acidic environment in the parietal cells where it inhibits the H+, K+-ATPase enzyme, i.e. the final stage in the production of hydrochloric acid in the stomach. The inhibition is dose- dependent and affects both basal and stimulated acid secretion. In most patients, freedom from symptoms is achieved within 2 weeks. As with other proton pump inhibitors and H2 receptor inhibitors, treatment with pantoprazole reduces acidity in the stomach and thereby increases gastrin in proportion to the reduction in acidity. The increase in gastrin is reversible. Since pantoprazole binds to the enzyme distal to the cell receptor level, it can inhibit hydrochloric acid secretion independently of stimulation by other substances (acetylcholine, histamine, gastrin). The effect is the same whether the product is given orally or intravenously. The fasting gastrin values increase under pantoprazole. On short- term use, in most cases they do not exceed the upper limit of normal. During long-term treatment, gastrin levels double in most cases. An excessive increase, however, occurs only in isolated cases. As a result, a mild to moderate increase in the number of specific endocrine (ECL) cells in the stomach is observed in a minority of cases during long term treatment (simple to adenomatoid hyperplasia). During treatment with antisecretory medicinal products, serum gastrin increases in response to the decreased gastric acidi Leggi il documento completo