Land: Malasía
Tungumál: enska
Heimild: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
LINCOMYCIN HCL; SPECTINOMYCIN HCL
RANGE PHARMA SDN. BHD.
LINCOMYCIN HCL; SPECTINOMYCIN HCL
10.00 kg; 25.00 kg
RANGE PHARMA SDN. BHD.
LINCO ACTINMIX POWDER DESCRIPTION AND COMPOSITION Linco Actinmix is a white to off white powder. Each kg contains 22g Lincomycin and 22g Spectinomycin PHARMACODYNAMICS Lincomycin It is effective primarily against gram-positive pathogens, and not effective against gram-negative bacteria such as Neisserie gonorrhoeae or Neisseria meningitidis. The antibacterial activity of Lincomycin hydrochloride is similar to the group of macrolide antibiotics to which erythromycin belongs. Lincomycin is one of the antibiotics of the lincosamines class. It was first isolated beginning of the 1960s from the microorganism Streptomyces lincolnensis, named after the Licoln, Nebraska, where this microorganism was first analyzed. Lincomycin hydrochloride is used against susceptible strains of streptococci, pneumococci, and staphylococci which usually can also be treated with penicillin or erythromycin. Generally, lincomycin acts by blocking protein synthesis by binding to the 50S subunit of the ribosome and blocking peptidyltransferase reaction, thereby inhibiting protein synthesis of the cell. It is generally regarded as a bacteriostatic compound. Spectinomycin Spectinomycin is an aminocyclitol antibiotic produced by the bacterium Streptomyces spectabilis. It is active against a variety of aerobic gram- negative and gram-positive organisms, as well as Mycoplasma species. Spectinomycin is used clinically, primarily for its activity against gram- negative organisms; some gram-positive organisms may also be susceptible to this agent. It has in vitro and in vivo activity against Mannheimia (Pasteurella) haemolytica, Pasteurella multocida, and Haemophilus somnus, but anaerobic organisms are generally resistant. Spectinomycin is usually bacteriostatic at therapeutic doses. As an aminocyclitol antibiotic, spectinomycin is structurally and functionally similar to the aminoglycoside antibiotics, which are also aminocyclitols. Spectinomycin lacks the toxic effects of the aminoglycoside antibiotics; however, its use is limited by the ready devel Lestu allt skjalið