PANECTYL TABLET

Negara: Kanada

Bahasa: Inggris

Sumber: Health Canada

Bahan aktif:

TRIMEPRAZINE (TRIMEPRAZINE TARTRATE)

Tersedia dari:

SEARCHLIGHT PHARMA INC

Kode ATC:

R06AD01

INN (Nama Internasional):

ALIMEMAZINE

Dosis:

2.5MG

Bentuk farmasi:

TABLET

Komposisi:

TRIMEPRAZINE (TRIMEPRAZINE TARTRATE) 2.5MG

Rute administrasi :

ORAL

Unit dalam paket:

100

Jenis Resep:

Prescription

Area terapi:

PHENOTHIAZINE DERIVATIVES

Ringkasan produk:

Active ingredient group (AIG) number: 0106200001; AHFS:

Status otorisasi:

APPROVED

Tanggal Otorisasi:

2000-11-06

Karakteristik produk

PRODUCT MONOGRAPH
PR
PANECTYL
TRIMEPRAZINE TARTRATE TABLETS
2.5 MG AND 5 MG TRIMEPRAZINE (AS TRIMEPRAZINE TARTRATE) TABLETS
MANUFACTURER STANDARD
ANTIPRURITIC - ANTIHISTAMINIC
Searchlight Pharma Inc.
1600 Notre-Dame West, suite 312
Montreal, Quebec
H3J 1M1
Date of Preparation:
OCT 17, 2022
Submission Control No.: 267388
2
STRUCTURAL FORMULA AND CHEMISTRY
Neutral tartrate of 10-[3-(2-methyl) dimethylaminopropyl]
phenothiazine. Its structural formula
may be represented as follows:
White, non hygroscopic, light-sensitive, crystalline powder. Melting
range, between 160

and
164

C. Freely soluble in water, soluble in alcohol, sparingly soluble in
chloroform and very
slightly soluble in ether and benzene.
Molecular weight : 746.97
ACTION
Panectyl is a phenothiazine derivative with reduced central activity
and enhanced antihistaminic
and antipruritic effects. It has marked sedative, antiserotonin,
antispasmodic and antiemetic
properties but has only a weak effect on the autonomic nervous system.
INDICATIONS
_Pruritus _regardless of site or etiology such as may occur in :
neurodermatitis, eczema, urticaria,
pruritus
ani,
pruritus
vulvae,
drug
eruption,
dermatitis
herpetiformis,
insect
bites,
contact
dermatitis; pruritus due to non-dermatological conditions : chicken
pox, measles, Hodgkin’s
disease, obstructive jaundice, diabetes, zona.
_Cough _ of various etiologies such as may occur in : acute or chronic
conditions of the upper
respiratory tract, persistent cough, bronchial irritation, whooping
cough, asthma-like dyspnea,
asthma, hay fever.
3
CONTRAINDICATIONS
States of CNS depression due to barbiturates, alcohol, narcotics or
analgesics. Cases with a history
of blood dyscrasias or severe allergic reactions related to
trimeprazine or other phenothiazines.
Trimeprazine is contraindicated for use in children less than two
years of age. (see Warnings
section).
WARNINGS
Patients should be advised against driving or engaging in activities
requiring complete mental
alertness or physical co-ordination, until their res