Negara: Inggris
Bahasa: Inggris
Sumber: myHealthbox
Desflurane
Piramal Healthcare UK Limited
N01AB07
Desflurane
100% (v/v)
Inhalation vapour liquid
Inhalation
boxes of 6
POM - Prescription Only Medicine
Piramal Healthcare UK Limited
Nervous system; anesthetics; general; Halogenated hydrocarbons
It is indicated as an inhalation agent for induction and maintenance of general anesthesia for inpatient and outpatient surgery in adults and for the maintenance of anaesthesia in infants and children.
Authorised
2015-05-14
BARCODE 9.75” X 17.25” (FRONT SIDE) 9.75” X 17.25” (BACK SIDE) READ ALL OF THIS LEAFLET CAREFULLY BEFORE YOU START USING THIS MEDICINE BECAUSE IT CONTAINS IMPORTANT INFORMATION FOR YOU. - Keep this leaflet. You may need to read it again. - If you have any further questions, ask your doctor, pharmacist or nurse. - If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4. WHAT IS IN THIS LEAFLET 1. What Desflurane is and what it is used for 2. What you need to know before Desflurane is used 3. How to use Desflurane 4. Possible side effects 5. How to store Desflurane 6. Contents of the pack and other information 1. WHAT DESFLURANE IS AND WHAT IT IS USED FOR Desflurane Inhalation, liquid contains desflurane. Desflurane is a general anaesthetic used in surgery. It is an inhalation anaesthetic (it is given to you as a vapour for you to breathe in). Breathing in desflurane vapour causes you to fall into a deep sleep. It also maintains a deep sleep (general anaesthesia) during which you can undergo surgery. In adults, Desflurane is used for induction and maintenance of anaesthesia. In infants and children, it is used for maintenance of anaesthesia only. 2. WHAT YOU NEED TO KNOW BEFORE DESFLURANE IS USED DESFLURANE MUST NOT BE USED: - if you have or have ever had medical reasons for not receiving general anaesthetics. - if you are allergic to halogenated anesthetics. - if you or any member of your family has experienced a rapid and significant rise in body temperature during an operation (a condition called malignant hyperthermia). - if you are a child to bring on (induce) anaesthesia because of the significant risk of laryngospasm Baca dokumen lengkapnya
SUMMARY OF PRODUCT CHARACTERISTICS 1 NAME OF THE MEDICINAL PRODUCT Desflurane 100% (v/v) Inhalation Vapour, liquid 2 QUALITATIVE AND QUANTITATIVE COMPOSITION Desflurane 100% (v/v) 3 PHARMACEUTICAL FORM Inhalation vapour liquid Clear, colourless, liquid 4 CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS Desflurane is indicated as an inhalation agent for induction and maintenance of general anesthesia for inpatient and outpatient surgery in adults and for the maintenance of anaesthesia in infants and children. 4.2 POSOLOGY AND METHOD OF ADMINISTRATION Desflurane should be administered by persons trained in the administration of general anaesthesia using a vaporizer specifically designed and calibrated for use with desflurane. Equipment for maintenance of a patent airway, artificial ventilation, oxygen enrichment and circulatory resuscitation must be immediately available. Posology The administration of general anaesthesia must be individualized based on the patient’s response. It is determined depending on the desired effect, taking into consideration of the patient’s age and his clinical status. MAC-values (minimum alveolar concentration at which 50% of patients show no response to a standardized surgical incision) for desflurane decrease with increasing patient age. The dose of desflurane should be adjusted accordingly. The percentage concentration of desflurane corresponding to 1 MAC has been determined within carrier gas as listed in Table 1 below. TABLE 1 PERCENTAGE CONCENTRATION OF DESFLURANE corresponding to 1 MAC ACCORDING TO PATIENT AGE AND INHALATION MIXTURE (MEAN ± SD) Age N * 100 % Oxygen N * 60% Nitrous Oxide/ 40% Oxygen 2 weeks 6 9.2 ± 0.0 - - 10 weeks 5 9.4 ± 0.4 - - 9 months 4 10.0 ± 0.7 5 7.5 ± 0.8 2 years 3 9.1 ± 0 Baca dokumen lengkapnya