AURO-FAMCICLOVIR 125 famciclovir 125 mg tablets blister pack

Negara: Australia

Bahasa: Inggris

Sumber: Department of Health (Therapeutic Goods Administration)

Bahan aktif:

famciclovir

Tersedia dari:

Fair-Med Healthcare Australia Pty Ltd

INN (Nama Internasional):

Famciclovir

Status otorisasi:

Registered

Selebaran informasi

AURO-FAMCICLOVIR
CONSUMER MEDICINE INFORMATION
Ver 1.4
Page 1 of 5
AURO-FAMCICLOVIR 125, 250 & 500
Famciclovir
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions
about
AURO-
FAMCICLOVIR.
It does not contain all the available
information.
It
does
not
take
the
place of talking to your pharmacist
or doctor.
All
medicines
have
risks
and
benefits. Your pharmacist or doctor
have weighed the risks of you taking
AURO-FAMCICLOVIR against the
benefits it can provide.
IF YOU HAVE ANY CONCERNS ABOUT
THIS MEDICINE, ASK YOUR PHARMACIST
OR DOCTOR.
KEEP THIS LEAFLET WITH THE MEDICINE.
You may need to read it again.
WHAT
AURO-FAMCICLOVIR
IS USED FOR
SHINGLES
AURO-FAMCICLOVIR
is
an
antiviral
medicine
that
is
used
to
treat
shingles
in
adults
and
adolescents.
Shingles is a condition that is caused
by
a
herpes
virus
called
varicella
zoster,
the
same
virus
that
causes
chicken pox. The virus can become
active again in the body, even after
many
years,
resulting
in
shingles,
The main symptom is a rash that can
cause pain, burning and blisters.
Although
AURO-FAMCICLOVIR
does not cure the viral infection, it
helps to relieve the symptoms and
shorten their duration.
The best results are obtained if the
medicine
is
started
as
soon
as
possible
after
the
first
symptoms
begin to appear.
GENITAL HERPES
AURO-FAMCICLOVIR is used to
treat outbreaks of genital herpes and
also to suppress (prevent) recurrent
outbreaks of the condition.
Genital
herpes
is
a viral
infection
caused by herpes simplex 1 or herpes
simplex 2. It is usually transmitted
through sexual contact.
Symptoms include tingling, burning
or itching of the genitals, followed
by blisters that may be painful.
People who have frequent episodes
of
genital
herpes
can
also
take
AURO-FAMCICLOVIR
to
help
prevent the attacks.
Taking
AURO-FAMCICLOVIR
does not prevent you from spreading
the herpes virus to another person.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY THIS MEDICINE
HAS BEEN PRESCRIBED FOR YOU.
Your doctor may have prescribed it
for

Karakteristik produk

Product Information:
AURO-FAMCICLOVIR (Famciclovir Tablets 125, 250 & 500 mg)
Ver 1.3
Page 1 of 17
PRODUCT INFORMATION
AURO-FAMCICLOVIR 125 (125 MG FAMCICLOVIR TABLETS)
AURO-FAMCICLOVIR 250 (250 MG FAMCICLOVIR TABLETS)
AURO-FAMCICLOVIR 500 (500 MG FAMCICLOVIR TABLETS)
NAME OF THE MEDICINE
Famciclovir
CHEMICAL NAME:
9-(4-acetoxy-3-acetoxymethylbut-1-yl)-2-aminopurine
MOLECULAR FORMULA:
C
14
H
19
N
5
O
4
MOLECULAR WEIGHT:
321.3
CAS REGISTRY NUMBER:
104227-87-4
DESCRIPTION
Famciclovir is a synthetic guanine derivative. It is a white to pale
yellow crystalline solid.
AURO-FAMCICLOVIR is available as tablets containing 125, 250 & 500 mg
of famciclovir.
AURO-FAMCICLOVIR
tablets
contain
the
following
inactive
ingredients:
Sodium
starch
glycollate,
lactose
anhydrous,
hydroxypropylcellulose,
magnesium
stearate,
hypromellose,
macrogol 400 and titanium dioxide.
PHARMACOLOGY
PHARMACODYNAMICS
Pharmacotherapeutic group: Oral antiviral agent, ATC code: JO5A B09
VIROLOGY
Famciclovir is the oral form of the antiviral compound: penciclovir.
Famciclovir is rapidly
converted
_in vivo_
into penciclovir, which has demonstrable
_in vitro_
activity against herpes
Product Information:
AURO-FAMCICLOVIR (Famciclovir Tablets 125, 250 & 500 mg)
Ver 1.3
Page 2 of 17
simplex viruses (HSV types 1 and 2) and varicella zoster virus (VZV).
The antiviral effect of
orally administered famciclovir has been demonstrated in several
animal models: this effect is
due to
_in vivo_
conversion to penciclovir.
Penciclovir targets virus-infected cells where it is rapidly converted
into penciclovirtriphosphate
(mediated via virus-induced thymidine kinase). The triphosphate
inhibits viral DNA polymerase
by competition with deoxyguanosine triphosphate and is incorporated
into the extending DNA
chain, preventing significant chain elongation. Consequently, viral
DNA synthesis and, therefore,
viral replication are inhibited.
This triphosphate persists in infected cells in excess of 12 hours.
The long intracellular half-life of
penciclovir triphosphate ensures prolo