Country: Ավստրալիա
language: անգլերեն
source: Department of Health (Therapeutic Goods Administration)
famciclovir
Fair-Med Healthcare Australia Pty Ltd
Famciclovir
Registered
AURO-FAMCICLOVIR CONSUMER MEDICINE INFORMATION Ver 1.4 Page 1 of 5 AURO-FAMCICLOVIR 125, 250 & 500 Famciclovir CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about AURO- FAMCICLOVIR. It does not contain all the available information. It does not take the place of talking to your pharmacist or doctor. All medicines have risks and benefits. Your pharmacist or doctor have weighed the risks of you taking AURO-FAMCICLOVIR against the benefits it can provide. IF YOU HAVE ANY CONCERNS ABOUT THIS MEDICINE, ASK YOUR PHARMACIST OR DOCTOR. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT AURO-FAMCICLOVIR IS USED FOR SHINGLES AURO-FAMCICLOVIR is an antiviral medicine that is used to treat shingles in adults and adolescents. Shingles is a condition that is caused by a herpes virus called varicella zoster, the same virus that causes chicken pox. The virus can become active again in the body, even after many years, resulting in shingles, The main symptom is a rash that can cause pain, burning and blisters. Although AURO-FAMCICLOVIR does not cure the viral infection, it helps to relieve the symptoms and shorten their duration. The best results are obtained if the medicine is started as soon as possible after the first symptoms begin to appear. GENITAL HERPES AURO-FAMCICLOVIR is used to treat outbreaks of genital herpes and also to suppress (prevent) recurrent outbreaks of the condition. Genital herpes is a viral infection caused by herpes simplex 1 or herpes simplex 2. It is usually transmitted through sexual contact. Symptoms include tingling, burning or itching of the genitals, followed by blisters that may be painful. People who have frequent episodes of genital herpes can also take AURO-FAMCICLOVIR to help prevent the attacks. Taking AURO-FAMCICLOVIR does not prevent you from spreading the herpes virus to another person. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY THIS MEDICINE HAS BEEN PRESCRIBED FOR YOU. Your doctor may have prescribed it for read_full_document
Product Information: AURO-FAMCICLOVIR (Famciclovir Tablets 125, 250 & 500 mg) Ver 1.3 Page 1 of 17 PRODUCT INFORMATION AURO-FAMCICLOVIR 125 (125 MG FAMCICLOVIR TABLETS) AURO-FAMCICLOVIR 250 (250 MG FAMCICLOVIR TABLETS) AURO-FAMCICLOVIR 500 (500 MG FAMCICLOVIR TABLETS) NAME OF THE MEDICINE Famciclovir CHEMICAL NAME: 9-(4-acetoxy-3-acetoxymethylbut-1-yl)-2-aminopurine MOLECULAR FORMULA: C 14 H 19 N 5 O 4 MOLECULAR WEIGHT: 321.3 CAS REGISTRY NUMBER: 104227-87-4 DESCRIPTION Famciclovir is a synthetic guanine derivative. It is a white to pale yellow crystalline solid. AURO-FAMCICLOVIR is available as tablets containing 125, 250 & 500 mg of famciclovir. AURO-FAMCICLOVIR tablets contain the following inactive ingredients: Sodium starch glycollate, lactose anhydrous, hydroxypropylcellulose, magnesium stearate, hypromellose, macrogol 400 and titanium dioxide. PHARMACOLOGY PHARMACODYNAMICS Pharmacotherapeutic group: Oral antiviral agent, ATC code: JO5A B09 VIROLOGY Famciclovir is the oral form of the antiviral compound: penciclovir. Famciclovir is rapidly converted _in vivo_ into penciclovir, which has demonstrable _in vitro_ activity against herpes Product Information: AURO-FAMCICLOVIR (Famciclovir Tablets 125, 250 & 500 mg) Ver 1.3 Page 2 of 17 simplex viruses (HSV types 1 and 2) and varicella zoster virus (VZV). The antiviral effect of orally administered famciclovir has been demonstrated in several animal models: this effect is due to _in vivo_ conversion to penciclovir. Penciclovir targets virus-infected cells where it is rapidly converted into penciclovirtriphosphate (mediated via virus-induced thymidine kinase). The triphosphate inhibits viral DNA polymerase by competition with deoxyguanosine triphosphate and is incorporated into the extending DNA chain, preventing significant chain elongation. Consequently, viral DNA synthesis and, therefore, viral replication are inhibited. This triphosphate persists in infected cells in excess of 12 hours. The long intracellular half-life of penciclovir triphosphate ensures prolo read_full_document