Adrenaline

Negara: Australia

Bahasa: Inggris

Sumber: Department of Health (Therapeutic Goods Administration)

Bahan aktif:

Adrenaline

Selebaran informasi

ADRENALINE 1:10,000 INJECTION MINIJET® 

1 
ADRENALINE 1:10,000 
INJECTION MINIJET® 

CONSUMER MEDICINE INFORMATION 

You may have been given this product in an emergency situation by a
non-medical health professional. 

WHAT IS IN THIS 
LEAFLET? 

This leaflet contains information 
about Adrenaline 1:10,000 
Injection MINIJET.  Please read 
it carefully and keep it for future 
reference.  The information in 
this leaflet is only a summary 
and is not intended to replace 
advice from your doctor.   

Please consult your doctor or 
pharmacist if you have any 
comments or questions. 

WHAT IS 
ADRENALINE? 

Adrenaline is a chemical which 
is produced naturally by our 
bodies.  It helps to regulate 
most of the important functions 
such as heart rate, blood 
pressure and breathing.  When 
we have a fright or have to fight 
or run, extra adrenaline is 
released into our blood.  As this 
adrenaline circulates round the 
body it makes our heart beat 
faster, helps us to get more air 
into our lungs and increases the 
blood supply to the muscles.  
This helps us to cope with 
emergencies and is why we 
often get palpitations when we 
are frightened. Adrenaline 
injections are used to treat 
some emergency situations 
which can occur in the heart and 
lungs.  It can only be given by 
injection and it acts very quickly. 

WHEN IS ADRENALINE 
USED? 

Adrenaline injections are only 
used in medical emergencies.  
They are not used as regular 
treatment.   

Adrenaline 1:10,000 is used in 
people whose hearts have 
suddenly stopped (cardiac 
arrest).  The adrenaline can 
help to restart the heart and 
stimulates it to beat strongly. 

As adrenaline is only used in 
medical emergencies, the 
injection may be given by 
paramedical personnel such as 
ambulance or nursing staff. 

WHO SHOULD NOT 
HAVE ADRENALINE 
INJECTIONS? 

As adrenaline is an emergency 
life-saving product it should not 
be withhel

Karakteristik produk

 
1 
ADRENALINE HYDROCHLORIDE INJECTION

ADRENALINE 1:10 000 

PRODUCT INFORMATION 

DESCRIPTION 
Adrenaline is (R)-1-(3,4-dihydroxyphenyl)-2-methylaminoethanol; C
9
H
13
NO
3
.  It is a white odourless crystalline 
powder, soluble in solutions of mineral acids and alkalis.  CAS
51-43-4.  Its chemical structure is: 

Adrenaline 1:10,000 is a sterile solution of adrenaline
hydrochloride in water containing adrenaline 
hydrochloride 0.1 mg/mL and not more than 0.2% sulfur dioxide from
an equivalent amount of sodium bisulfite 
as an antioxidant.  The solution also contains sodium chloride,
sodium citrate, citric acid monohydrate and 
hydrochloric acid.  The solution contains no antimicrobial
preservatives. 

PHARMACOLOGY 
Adrenaline is a direct-acting sympathomimetic agent exerting its
effect on alpha and beta adrenoreceptors.  
Major effects are increased systolic blood pressure, reduced
diastolic pressure, tachycardia, hyperglycaemia 
and hypokalaemia.  It is a powerful cardiac stimulant.
 It has vasopressor properties, an antihistaminic action 
and is a bronchodilator.  Its action is rapid in onset and of short
duration. 

Adrenaline is rapidly distributed to the heart, spleen, several
glandular tissues and adrenergic nerves.  It 
crosses the placenta and is excreted in breast milk.  It is
approximately 50% bound to plasma proteins.  The 
onset of action is rapid and after intravenous infusion the half life
is approximately 5-10 minutes. 

Adrenaline is rapidly metabolised in the liver and tissues.  Up
to 90% of the IV dose is excreted as metabolites 
in the urine. 

INDICATIONS 
Adjunctive use in the management of cardiac arrest. 

CONTRAINDICATIONS 
Contraindications are relative as this product is intended for use in
life-threatening emergencies. 

The following contraindications should be considered: hyperthyroidism,
hypertension, ischaemic heart disease, 
diabetes mellitus, narrow angle glaucoma and known