Land: Australien
Sprache: Englisch
Quelle: Department of Health (Therapeutic Goods Administration)
Adrenaline
ADRENALINE 1:10,000 INJECTION MINIJET® 1 ADRENALINE 1:10,000 INJECTION MINIJET® CONSUMER MEDICINE INFORMATION You may have been given this product in an emergency situation by a non-medical health professional. WHAT IS IN THIS LEAFLET? This leaflet contains information about Adrenaline 1:10,000 Injection MINIJET. Please read it carefully and keep it for future reference. The information in this leaflet is only a summary and is not intended to replace advice from your doctor. Please consult your doctor or pharmacist if you have any comments or questions. WHAT IS ADRENALINE? Adrenaline is a chemical which is produced naturally by our bodies. It helps to regulate most of the important functions such as heart rate, blood pressure and breathing. When we have a fright or have to fight or run, extra adrenaline is released into our blood. As this adrenaline circulates round the body it makes our heart beat faster, helps us to get more air into our lungs and increases the blood supply to the muscles. This helps us to cope with emergencies and is why we often get palpitations when we are frightened. Adrenaline injections are used to treat some emergency situations which can occur in the heart and lungs. It can only be given by injection and it acts very quickly. WHEN IS ADRENALINE USED? Adrenaline injections are only used in medical emergencies. They are not used as regular treatment. Adrenaline 1:10,000 is used in people whose hearts have suddenly stopped (cardiac arrest). The adrenaline can help to restart the heart and stimulates it to beat strongly. As adrenaline is only used in medical emergencies, the injection may be given by paramedical personnel such as ambulance or nursing staff. WHO SHOULD NOT HAVE ADRENALINE INJECTIONS? As adrenaline is an emergency life-saving product it should not be withhel Lesen Sie das vollständige Dokument
1 ADRENALINE HYDROCHLORIDE INJECTION ADRENALINE 1:10 000 PRODUCT INFORMATION DESCRIPTION Adrenaline is (R)-1-(3,4-dihydroxyphenyl)-2-methylaminoethanol; C 9 H 13 NO 3 . It is a white odourless crystalline powder, soluble in solutions of mineral acids and alkalis. CAS 51-43-4. Its chemical structure is: Adrenaline 1:10,000 is a sterile solution of adrenaline hydrochloride in water containing adrenaline hydrochloride 0.1 mg/mL and not more than 0.2% sulfur dioxide from an equivalent amount of sodium bisulfite as an antioxidant. The solution also contains sodium chloride, sodium citrate, citric acid monohydrate and hydrochloric acid. The solution contains no antimicrobial preservatives. PHARMACOLOGY Adrenaline is a direct-acting sympathomimetic agent exerting its effect on alpha and beta adrenoreceptors. Major effects are increased systolic blood pressure, reduced diastolic pressure, tachycardia, hyperglycaemia and hypokalaemia. It is a powerful cardiac stimulant. It has vasopressor properties, an antihistaminic action and is a bronchodilator. Its action is rapid in onset and of short duration. Adrenaline is rapidly distributed to the heart, spleen, several glandular tissues and adrenergic nerves. It crosses the placenta and is excreted in breast milk. It is approximately 50% bound to plasma proteins. The onset of action is rapid and after intravenous infusion the half life is approximately 5-10 minutes. Adrenaline is rapidly metabolised in the liver and tissues. Up to 90% of the IV dose is excreted as metabolites in the urine. INDICATIONS Adjunctive use in the management of cardiac arrest. CONTRAINDICATIONS Contraindications are relative as this product is intended for use in life-threatening emergencies. The following contraindications should be considered: hyperthyroidism, hypertension, ischaemic heart disease, diabetes mellitus, narrow angle glaucoma and known Lesen Sie das vollständige Dokument