Country: Ամերիկայի Միացյալ Նահանգներ
language: անգլերեն
source: NLM (National Library of Medicine)
Phenylbutazone (UNII: GN5P7K3T8S) (Phenylbutazone - UNII:GN5P7K3T8S)
Vet One
Phenylbutazone
Phenylbutazone 1 g in 3.027 g
PRESCRIPTION
ACTIONS AND USES: Kuzell (1,2,3), Payne (4), Flemming (5) and Denko (6), demonstrated clinical effectiveness of phenylbutazone in acute rheumatism, gout, gouty arthritis and various other rheumatoid diseases in man. Anti-inflammatory activity has been well established by Fabre (7), Domenjoz (8), Wilhelmi (9), and Yourish (10). Lieberman (11) reported on the effective use of phenylbutazone in the treatment of conditions of the musculoskeletal system in dogs, including posterior paralysis associated with intervertebral disc syndrome, fractures, arthritis and injuries to the limbs and joints. Joshua (12) observed objective improvement without toxicity following long-term therapy of two aged arthritic dogs. Ogilvie and Sutter (13) reported rapid response to phenylbutazone therapy in a review of 19 clinical cases including posterior paralysis, posterior weakness, arthritis, rheumatism and other conditions associated with lameness and musculoskeletal weakness. Camberos (14) reported favorable results with pheny
HOW SUPPLIED: BUTATRON (Phenylbutazone Tablets, U.S.P.) are supplied in the following tablet concentrations and package sizes: 100 mg tablets.......................Bottles of 1000 tablets 1 gram tablets........................Bottles of 100 tablets
New Animal Drug Application
PHENYLBUTAZONE - PHENYLBUTAZONE TABLET VET ONE ---------- CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION: Phenylbutazone is a non-hormonal, anti-inflammatory agent. Chemically, it is described as 4-Butyl-1,2- diphenyl-3,5 pyrazolidinedione, a synthetic pyrazolone derivative, entirely unrelated to the steroid compounds. ACTIONS AND USES: Kuzell (1,2,3), Payne (4), Flemming (5) and Denko (6), demonstrated clinical effectiveness of phenylbutazone in acute rheumatism, gout, gouty arthritis and various other rheumatoid diseases in man. Anti-inflammatory activity has been well established by Fabre (7), Domenjoz (8), Wilhelmi (9), and Yourish (10). Lieberman (11) reported on the effective use of phenylbutazone in the treatment of conditions of the musculoskeletal system in dogs, including posterior paralysis associated with intervertebral disc syndrome, fractures, arthritis and injuries to the limbs and joints. Joshua (12) observed objective improvement without toxicity following long-term therapy of two aged arthritic dogs. Ogilvie and Sutter (13) reported rapid response to phenylbutazone therapy in a review of 19 clinical cases including posterior paralysis, posterior weakness, arthritis, rheumatism and other conditions associated with lameness and musculoskeletal weakness. Camberos (14) reported favorable results with phenylbutazone following intermittent treatment of thoroughbred horses and arthritis and chronic arthrosis (e.g. osteoarthritis of medical and distal bones of the hock, arthritis of the stifle and hip, arthrosis of the spine and generalized arthritis). Results were less favorable in cases of traumatism, muscle rupture, strains and inflammatory conditions of the third phalanx. Sutter (15) reported favorable responses in chronic equine arthritis, fair results in a severely bruised mare, and poor results in two cases where the condition was limited to the third phalanx. INDICATIONS: Phenylbutazone possesses non-hormonal, anti-inflammatory activity read_full_document