PHENYLBUTAZONE- phenylbutazone tablet

País: Estats Units

Idioma: anglès

Font: NLM (National Library of Medicine)

ingredients actius:

Phenylbutazone (UNII: GN5P7K3T8S) (Phenylbutazone - UNII:GN5P7K3T8S)

Disponible des:

Vet One

Designació comuna internacional (DCI):

Phenylbutazone

Composición:

Phenylbutazone 1 g in 3.027 g

tipo de receta:

PRESCRIPTION

indicaciones terapéuticas:

ACTIONS AND USES: Kuzell (1,2,3), Payne (4), Flemming (5) and Denko (6), demonstrated clinical effectiveness of phenylbutazone in acute rheumatism, gout, gouty arthritis and various other rheumatoid diseases in man.  Anti-inflammatory activity has been well established by Fabre (7), Domenjoz (8), Wilhelmi (9), and Yourish (10). Lieberman (11) reported on the effective use of phenylbutazone in the treatment of conditions of the musculoskeletal system in dogs, including posterior paralysis associated with intervertebral disc syndrome, fractures, arthritis and injuries to the limbs and joints.  Joshua (12) observed objective improvement without toxicity following long-term therapy of two aged arthritic dogs.  Ogilvie and Sutter (13) reported rapid response to phenylbutazone therapy in a review of 19 clinical cases including posterior paralysis, posterior weakness, arthritis, rheumatism and other conditions associated with lameness and musculoskeletal weakness.  Camberos (14) reported favorable results with pheny

Resumen del producto:

HOW SUPPLIED: BUTATRON (Phenylbutazone Tablets, U.S.P.) are supplied in the following tablet concentrations and package sizes: 100 mg tablets.......................Bottles of 1000 tablets 1 gram tablets........................Bottles of 100 tablets

Estat d'Autorització:

New Animal Drug Application

Fitxa tècnica

PHENYLBUTAZONE - PHENYLBUTAZONE TABLET
VET ONE
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CAUTION:
Federal law restricts this drug to use by or on the order of a
licensed veterinarian.
DESCRIPTION:
Phenylbutazone is a non-hormonal, anti-inflammatory agent. Chemically,
it is described as 4-Butyl-1,2-
diphenyl-3,5 pyrazolidinedione, a synthetic pyrazolone derivative,
entirely unrelated to the steroid
compounds.
ACTIONS AND USES:
Kuzell (1,2,3), Payne (4), Flemming (5) and Denko (6), demonstrated
clinical effectiveness of
phenylbutazone in acute rheumatism, gout, gouty arthritis and various
other rheumatoid diseases in man.
Anti-inflammatory activity has been well established by Fabre (7),
Domenjoz (8), Wilhelmi (9), and
Yourish (10).
Lieberman (11) reported on the effective use of phenylbutazone in the
treatment of conditions of the
musculoskeletal system in dogs, including posterior paralysis
associated with intervertebral disc
syndrome, fractures, arthritis and injuries to the limbs and joints.
Joshua (12) observed objective
improvement without toxicity following long-term therapy of two aged
arthritic dogs. Ogilvie and
Sutter (13) reported rapid response to phenylbutazone therapy in a
review of 19 clinical cases including
posterior paralysis, posterior weakness, arthritis, rheumatism and
other conditions associated with
lameness and musculoskeletal weakness.
Camberos (14) reported favorable results with phenylbutazone following
intermittent treatment of
thoroughbred horses and arthritis and chronic arthrosis (e.g.
osteoarthritis of medical and distal bones
of the hock, arthritis of the stifle and hip, arthrosis of the spine
and generalized arthritis). Results were
less favorable in cases of traumatism, muscle rupture, strains and
inflammatory conditions of the third
phalanx. Sutter (15) reported favorable responses in chronic equine
arthritis, fair results in a severely
bruised mare, and poor results in two cases where the condition was
limited to the third phalanx.
INDICATIONS:
Phenylbutazone possesses non-hormonal, anti-inflammatory activity