WeissNicarb 25% ww Premix Powder

Ország: Malajzia

Nyelv: angol

Forrás: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktív összetevők:

NICARBAZINE

Beszerezhető a:

Weissen Company (m) Sdn. Bhd.

INN (nemzetközi neve):

NICARBAZINE

db csomag:

25 kg

Gyártó:

Weissen Company (m) Sdn. Bhd.

Termékjellemzők

PACKAGE INSERT
Brand or product name
WeissNicarb 25% w/w Premix Powder
Name and Strength of
Active Substance
Nicarbazine……..250 mg/g
Product Description
Green Yellow Powder
Pharmacodynamics
Nicarbazin is a broad-spectrum chemical anticoccidial agent
used to prevent disease and treat infection in food-producing
poultry. The drug residue is composed of equimolar quantities of
4,4-dinitrocarbanilide
(DNC)
and
2-hydroxy-4,6-dimethyl
pyrimidine (HDP), with DNC serving as the primary component
for
tracking
of
the
residue
in
edible
tissues,
including
fat,
muscle, liver, and kidney, and in eggs.
Pharmacokinetics
Nicarbazin, when ingested, is rapidly split in its two components
2-hydroxy-4,6-dimethylpyrimidine (HDP) and dinitrocarbanilide
(DNC) which behave independently. Liver is the target tissue.
Dinitrocarbanilide (DNC) residues decline rapidly from tissues
following
nicarbazin
withdrawal.
Dinitrocarbanilide
(DNC)
appears
as
the
marker
residue.
2-hydroxy-4,6-
dimethylpyrimidine (HDP) -related residues are much lower (by
two
orders
of
magnitude)
than
those
derived
from
dinitrocarbanilide (DNC). The metabolic pathways in the turkey
are similar to those in the chicken.
Nicarbazin as such cannot appear as residue in tissues; only its
two individual components may generate residues.
Environmental Properties
(for product used directly in
the environment e.g.
medicine for fish)
N/A
Indication
Aid
in
preventing
outbreaks
of
cecal
(_Eimeria _
_tenella_)
and
intestinal (_E. acervulina, E. maxima, E. necatrix_ and _E. brunetti_)
coccidiosis.
Recommended Dosage
125
grams
Nicarbazine
per
tonne
of
feed
(500
grams
WeissNicarb 25% w/w Premix Powder).
Mode of Administration
Oral Administration
Contra-indications
Do
not
use
in
know
cases
of
hypersensitivity
to
active
ingredient.
Warnings and Precautions
Feed continuously as sole ration from time chicks are placed on
litter until past the time when coccidiosis is ordinarily a hazard.
Do not use as a treatment for coccidiosis. Do not use in flushing
mashes. Do not feed to laying hens