FENFEDRIN CAPSULE

Ország: Malajzia

Nyelv: angol

Forrás: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktív összetevők:

PSEUDOEPHEDRINE HYDROCHLORIDE; CHLORPHENIRAMINE MALEATE

Beszerezhető a:

XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD

INN (nemzetközi neve):

PSEUDOEPHEDRINE HYDROCHLORIDE; CHLORPHENIRAMINE MALEATE

db csomag:

7 Capsules; 35 Capsules

Gyártó:

XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD

Betegtájékoztató

_Consumer Medication Information Leaflet (RiMUP)_
FENFEDRIN CAPSULE
Pseudoephedrine hydrochloride/Chlorpheniramine Maleate (60mg/4mg)
1
WHAT IS IN THIS LEAFLET
:
1.
What is Fenfedrin used for
2.
How Fenfedrin works
3.
Before you use Fenfedrin
4.
How to use Fenfedrin
5.
While you are using Fenfedrin
6.
Side effects
7.
Storage and disposal of Fenfedrin
8.
Product description
9.
Manufacturer and Product Registration
Holder
10.
Date of revision
WHAT IS FENFEDRIN USED FOR
It
is
used
to
relief
nose
congestion
in
common colds and help clear airway.
It provides temporary relief to runny nose,
sneezing and itching of
nose caused by
allergic
rhinitis
(inflammation
of
the
mucous membrane inside the nose) such as
hay fever.
HOW FENFEDRIN WORKS
Pseudoephedrine
is
a
decongestant.
It
works by narrowing the blood vessels in
the
nose
to
decrease
swelling
and
congestion.
Chlorpheniramine Maleate helps to reduce
secretion
in
the
nose
by
blocking
histamine, a natural substance produced in
the body during allergic reactions.
BEFORE YOU USE FENFEDRIN_ _
_When you must not use it_
Do not use Fenfedrin if you

are allergic to any ingredients in this
medicine.

are going to use it for children below 12
years old.
_Before you start to use it_
Tell your doctor or pharmacist before using
Fenfedrin if you:

are pregnant or plan to get pregnant.

are
breast-feeding
or
plan
to
start
breast-feeding.

are taking medicines for antidepressant,
e.g.
MAOIs
(monoamine
oxidase
inhibitors) or within two weeks from
stopping treatment.

have heart or metabolic problems, e.g.
asthma, high blood pressure, overactive
of thyroid gland.

have
prostate
enlargement
and/or
bladder disorder.

have epilepsy (seizure).

have glaucoma (increased pressure in
the eye).

have gastrointestinal problems such as
peptic
ulcer
or
pyloroduodenal
obstruction
(gastric
outflow
obstruction).
_Taking other medicines_
Tell your doctor or pharmacist if you are
taking or having recently taken any other
medicines. This includes any medicines
which you ha

Termékjellemzők

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-
-
-
-
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Important information. Please read carefully.
FENFEDRIN
TM
Capsules
Relieves nasal congestion in common colds and allergic rhinitis (eg.
hayfever).
COMPOSITION
Each capsule contains
Chlorpheniramine Maleate
Pseudoephedrine Hydrochloride
4mg
60mg
FE0201/FE0202-004
11.21
Pharmacodynamics
Chlorpheniramine Maleate belongs to the alkylamine antihistamines,
which are among the most active H1-blockers and are generally
effective in
relatively low doses. It is used to reduce rhinorrhoea and sneezing.
Pseudoephedrine is a sympathomimetic agent with direct and indirect
effects on adrenergic receptors. It is said to have less pressor
activity and
CNS effects than ephedrine of which it is a stereoisomer.
Pseudoephedrine hydrochloride is used as a nasal and bronchial
decongestant.
Both active ingredients are readily absorbed from the
gastro-intestinal tract.
Pseudoephedrine is resistant to metabolism by monoamine oxidase and up
to about 90% of a dose in 24 hours is largely excreted unchanged
in the urine. Less than 1% is excreted as nor-pseudoephedrine which is
pH dependent. The half-life of several hours is reduced in acid urine.
Chlorpheniramine
is
extensively
metabolised
to
polar
and
non-polar
metabolites.
The
excretion
of
the
unchanged
drug
is
increased
by
acidification of the urine and increased flow of urine. After daily
oral administration the forms excreted are about 20% unchanged drug,
20% as
monodesmethylchlorpheniramine, 5% as didesmethylchlorpheniramine. Less
than 1% is excreted through the faeces.
Pharmacokinetics
Both active ingredients are readily absorbed from the
gastro-intestinal tract.
Pseudoephedrine is resistant to metabolism by monoamine oxidase and up
to about 90% of a dose in 24 hours is largely excreted unchanged in
the urine. Less than 1% is excreted as nor-pseudoephedrine which is pH
dependent. The half-life of several hours is reduced in acid urine.
Chlorpheniramine
is
extensively
metabolised
to
polar
and
non-polar
metabolites.
The
excretion
of
the
unchanged
drug
is
increased
by
acidifi