Uphalexin Granules 125mg5ml

מדינה: מלזיה

שפה: אנגלית

מקור: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

מרכיב פעיל:

CEPHALEXIN MONOHYDRATE

זמין מ:

Duopharma Marketing Sdn. Bhd.

INN (שם בינלאומי):

CEPHALEXIN MONOHYDRATE

יחידות באריזה:

60 ml

תוצרת:

KOTRA PHARMA (M) SDN. BHD.

עלון מידע

_Consumer Medication Information Leaflet (RiMUP) _
UPHALEXIN GRANULES 125MG/5ML
Cephalexin (125mg/5ml)
1
WHAT IS IN THIS LEAFLET
1.
What
Uphalexin
Granules
125mg/5ml is used for.
2.
How
Uphalexin
Granules
125mg/5ml works.
3.
Before
you
use
Uphalexin
Granules 125mg/5ml.
4.
How to use Uphalexin Granules
125mg/5ml.
5.
While you are using it.
6.
Side effects.
7.
Storage
and
disposal
of
Uphalexin Granules 125mg/5ml.
8.
Product description.
9.
Manufacturer
and
Product
Registration Holder.
10.
Date of revision.
WHAT
UPHALEXIN
GRANULES
125MG/5ML IS USED FOR
Uphalexin Granules is an antibiotic
which is indicated in the treatment of
the following infections due to
susceptible microorganisms:
•
Respiratory tract infections
•
Otitis media (ear infection)
•
Bone infections
•
Genitourinary (urinary) tract
infections, including acute
prostatitis
HOW
UPHALEXIN
GRANULES
125MG/5ML WORKS
Uphalexin
Granules
125mg/5ml
suspension
consists
of
active
substance Cephalexin.
Cephalexin
is
an
antibiotic
that
belongs to the
group of
medicines
called
Cephalosporin.
These
medicines
work
by
killing
the
−
_Before you start to use it_
Tell your doctor if:
•
You
are
allergic
to
any
medicines, food and dyes.
•
You
are
taking
any
other
medicines
(including
those
not
prescribed by your doctor).
•
You have had an allergic reaction
to penicillins. There may be an
increased
risk
of
you
being
allergic
to
Uphalexin
Granules
125mg/5ml if you are allergic to
penicillin.
•
You are a patient with renal
impairment.
•
Pregnancy and lactation.
•
You need to perform some urine
or blood test.
•
You have history of diarrhea
associated with antibiotic used.
Please consult your doctor before start
to
use
Uphalexin
Granules
125mg/5ml if you are pregnant, plan
to become pregnant, breast-feeding or
intend to breast-feed. Your doctor will
have weighed the risks of you taking
Uphalexin
Granules
125mg/5ml
against the benefits they expect it will
have for you.
−
_Taking other medicines_
Tell your doctor if you are taking any
other medicines, includ

מאפייני מוצר

COMPOSITION
PHARMACOKINETICS
INDICATIONS
PHARMACODYNAMICS
Each 5ml contains
Cephalexin Monohydrate
equivalent to Cephalexin 125 mg
White colored powder which gives a beige colored suspension with
fruity flavor when
reconstituted.
Treatment of the following infections when caused by susceptible
strains of the
designated micro-organisms.
-
Respiratory Tract Infections caused by S.pneumoniae and group A -
Haemolytic
streptococci.
-
Otitis media due to S.pneumoniae, H.influenzae, staphylococci and/or
M.catarrhalis
- Bone infection caused by staphylococci and/or P.mirabilis
- Genitourinary Tract Infections, including acute prostatitis, caused
by E.coli,
P.mirabilis and Klebsiella spp.
- Dental infection caused by staphylococci and/or streptococci
Cephalexin is bactericidal; its action depending on its ability to
bind penicillin-binding
proteins located in bacterial cytoplasmic membranes. Cephalexin
inhibits synthesis of
bacterial septum and cell wall probably by acylation of
transpeptidases enzymes. These
enzymes are responsible for the cross linking of peptidoglycan chains,
which is
necessary for the bacterial cell wall strength and rigidity. Cell
division and growth are
also inhibited. Rapidly dividing bacteria are those most susceptible
to the action of
cephalexin.
Cephalexin is almost completely absorbed from the gastrointestinal
tract. If cephalexin
is taken with food, absorption may be delayed, but the total amount
absorbed is not
appreciably altered. It is widely distributed in the body but does not
enter the
cerebrospinal fluids in significant quantities. It is not metabolised.
About 80% or more
of a dose is excreted unchanged in the urine.
Contraindicated in patient hypersensitive to cephalosporin.
Cephalexin should be used with caution for patient with penicillin
sensitivity. False
positive urinary glucose and false positive Combs’ test have been
found during the
treatment of Cephalexin. Patients with renal impairment should be
given with caution.
Pseudomembranous colitis has been reported with nearly all