SODIUM CITRATE AND CITRIC ACID- sodium citrate and citric acid monohydrate solution

מדינה: ארצות הברית

שפה: אנגלית

מקור: NLM (National Library of Medicine)

מרכיב פעיל:

SODIUM CITRATE, UNSPECIFIED FORM (UNII: 1Q73Q2JULR) (ANHYDROUS CITRIC ACID - UNII:XF417D3PSL), ANHYDROUS CITRIC ACID (UNII: XF417D3PSL) (ANHYDROUS CITRIC ACID - UNII:XF417D3PSL)

זמין מ:

Cardinal Health

מסלול נתינה (של תרופות):

ORAL

סוג מרשם:

PRESCRIPTION DRUG

סממני תרפויטית:

Sodium Citrate and Citric Acid Oral Solution USP is an effective alkalinizing agent. It is useful in those conditions where long-term maintenance of an alkaline urine is desirable, and is of value in the alleviation of chronic metabolic acidosis, such as results from chronic renal insufficiency or the syndrome of renal tubular acidosis, especially when the administration of potassium salts is undesirable or contraindicated. This product is also useful for buffering and neutralizing gastric hydrochloric acid quickly and effectively. Sodium Citrate and Citric Acid Oral Solution USP is concentrated, and when administered after meals and before bedtime, allows one to maintain an alkaline urinary pH around the clock, usually without the necessity of a 2 A.M. dose. This product alkalinizes the urine without producing a systemic alkalosis in the recommended dosage. This product is highly palatable, pleasant tasting, and tolerable, even when administered for long periods. Patients on sodium-restricted diets or with s

leaflet_short:

Sodium Citrate and Citric Acid Oral Solution USP (colorless, grape flavor) is supplied in the following oral dosage forms: Overbagged with 5 cups per bag, (Unit dose cups of 30 mL) NDC 55154-9410-5. Keep tightly closed. Store at controlled room temperature, 20° -25° C (68° -77° F). Protect from freezing.

מצב אישור:

unapproved drug other

מאפייני מוצר

SODIUM CITRATE AND CITRIC ACID- SODIUM CITRATE AND CITRIC ACID
MONOHYDRATE SOLUTION
CARDINAL HEALTH
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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SODIUM CITRATE AND CITRIC ACID ORAL SOLUTION USP
A Sugar-Free Systemic Alkalizer
DESCRIPTION
Sodium Citrate and Citric Acid Oral Solution USP is a stable and
pleasant-tasting systemic alkalizer
containing sodium citrate and citric acid in a sugar-free base. It is
a nonparticulate neutralizing buffer.
Sodium Citrate and Citric Acid Oral Solution USP contains in each
teaspoonful (5 mL):
SODIUM CITRATE Dihydrate 500 mg (0.34 Molar)
CITRIC ACID Monohydrate 334 mg (0.32 Molar)
Each mL contains 1 mEq sodium ion and is equivalent to 1 mEq
bicarbonate (HCO3).
INACTIVE INGREDIENTS: Flavoring, polyethylene glycol, propylene
glycol, purified water, sodium
benzoate, and sorbitol solution.
CLINICAL PHARMACOLOGY
Sodium citrate is absorbed and metabolized to sodium bicarbonate, thus
acting as a systemic alkalizer.
The effects are essentially those of chlorides before absorption and
those of bicarbonates
subsequently. Oxidation is virtually complete so that less than 5% of
sodium citrate is excreted in the
urine unchanged.
INDICATIONS AND USAGE
Sodium Citrate and Citric Acid Oral Solution USP is an effective
alkalinizing agent. It is useful in those
conditions where long-term maintenance of an alkaline urine is
desirable, and is of value in the
alleviation of chronic metabolic acidosis, such as results from
chronic renal insufficiency or the
syndrome of renal tubular acidosis, especially when the administration
of potassium salts is undesirable
or contraindicated. This product is also useful for buffering and
neutralizing gastric hydrochloric acid
quickly and effectively.
Sodium Citrate and Citric Acid Oral Solution USP is concentrated, and
when administered after meals
and before bedtime, allows one to maintain an alkaline urinary pH
ar