RINALIX TABLET 2.5MG

מדינה: מלזיה

שפה: אנגלית

מקור: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

מרכיב פעיל:

INDAPAMIDE

זמין מ:

XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD

INN (שם בינלאומי):

INDAPAMIDE

יחידות באריזה:

30Tablet Tablets; 60Tablet Tablets; 90Tablet Tablets; 300Tablet Tablets; 28Tablet Tablets; 280Tablet Tablets

תוצרת:

XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD

עלון מידע

RINALIX TABLET 2.5MG
Each tablet contains Indapamide 2.5mg.
IN THIS LEAFLET:
•
_What is Rinalix used for _
•
_How Rinalix works _
•
_Before you take Rinalix _
•
_How to take Rinalix _
•
_While you are taking Rinalix _
•
_Possible side effects _
•
_How should you keep Rinalix _
•
_Product description_
_ _
WHAT IS RINALIX USED FOR
It
is
used
for
the
treatment
of
high
blood pressure (hypertension).
HOW RINALIX WORKS
Indapamide
belongs
to
thiazide
diuretics that acts directly on the kidney
to
increase
water
excretion
and
thus
decrease blood volume and pressure of
the blood vessels.
BEFORE YOU TAKE RINALIX
_WHEN YOU MUST NOT TAKE IT _
Do not take Rinalix if you:
•
are
allergic
(hypersensitivity)
to
indapamide,
other
sulfonamide-
derived drugs or any ingredients in
the medicines.
•
have severe liver disease.
•
have stroke.
•
experience absence of urine (anuria).
_BEFORE START TO TAKE IT _
Tell your doctor or pharmacist if you:
•
have liver and/or renal impairment.
•
have
high
uric
acid
level
(hyperuricemia) and gout.
•
have fluid and electrolyte imbalance.
•
have disorder of parathyroid glands
(hyperthyroidism)
•
are pregnant or plan to pregnant.
•
are breast-feeding or plan to start
breast-feeding.
_ _
_TAKING OTHER MEDICINES _
Tell your doctor or pharmacist if you
are taking or have recently taken any
other
medicines,
including
medicines
obtained without prescription.
HOW TO TAKE RINALIX
_HOW MUCH TO TAKE _
One tablet daily, with or without food.
_ _
_WHEN TO TAKE IT _
Preferably in the morning.
_HOW LONG TO TAKE IT _
Follow
the
prescription
from
your
doctor or pharmacist.
Ask your doctor or pharmacist before
prolonged use of this medicine.
_IF YOU FORGET TO TAKE IT _
Take
it
as
soon
as
you
remember,
unless it is nearly time for your next
dose, skip the missed dose. Then go on
as before. Never double up on the next
dose to make up for the one missed.
_IF YOU TAKE TOO MUCH _
Signs
of
overdose
include
nausea,
vomiting,
weakness,
gastrointestinal
disorders,
electrolyte
imbalance,
low

מאפייני מוצר

COMPOSITION
Each tablet contains: Indapamide 2.5 mg
PHARMACODYNAMICS
Indapamide is a diuretic with actions similar to those of the thiazide
diuretics. It acts
directly on the kidney to increase the excretion of sodium chloride
and water; it also
increases the excretion of K
+
.
PHARMACOKINETICS
Indapamide is rapidly and completely absorbed from the
gastro-intestinal tract. Peak
blood levels are obtained after 1 to 2
hours. Indapamide is strongly and
reversibly bound to
plasma protein and to erythrocytes. A minimum of 70% of a
single oral dose is eliminated by the kidneys and an additional 23% by
the
gastrointestinal tract. Indapamide is metabolised with 7% of the
unchanged
product found in the urine during the 48 hours following
administration. The
elimination half-life of Indapamide is approximately 15-18 hours.
Indapamide is
strongly and reversibly bound to plasma protein and to erythrocytes.
INDICATIONS
Rinalix
is
indicated
for
the
treatment
of essential hypertension, alone or in
combination with other antihypertensive drugs.
DOSAGE AND ADMINISTRATION
To be administered orally.
_Hypertension_: 2.5 mg daily, to be taken in the morning. The action
of Indapamide
is progressive and the reduction in blood pressure may continue and
not reach a
maximum until several months after the initiation of therapy. A larger
dose than 2.5
mg Indapamide is not recommended as there is no appreciable
antihypertensive
effect but a diuretic effect may become apparent.
CONTRAINDICATIONS
Anuria, stroke, recent cerebrovascular accident, severe hepatic
insufficiency,
known hypersensitivity to indapamide or to other sulfonamide-derived
drugs.
PRECAUTIONS / WARNINGS
_Hypokalemia, Hyponatremia, and Other Fluid and Electrolyte
imbalances: _Periodic
determinations of serum electrolytes should be performed at
appropriate intervals.
Patients should be observed for clinical signs of fluid or electrolyte
imbalance, such
as hyponatremia, hypochloremic alkalosis, or hypokalemia.
Pharmacode Area
_Hyperuricemia and Gout_: Serum concentrations of uri