מדינה: ארמניה
שפה: אנגלית
מקור: Դեղերի և բժշկական տեխնոլոգիաների փորձագիտական կենտրոնի գործունեության Հայաստանի Հանրապետությունում
doxofylline
M & H Manufacturing Co. Ltd.
doxofylline
400mg
tablets
Prescription
PUROXAN TABLET SUMMARY OF PRODUCT CHARACTERISTICS (DOXOFYLLINE 400 MG TABLET) APPENDIX 1.9 1. NAME OF THE MEDICINAL PRODUCT Puroxan 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Each tablet contains Doxofylline 400 mg For excipients, see 6.1. 3. DOSAGE FORM Tablets 4. CLINICAL CHARACTERISTICS 4.1 THERAPEUTIC INDICATIONS PUROXAN is indicated for the treatment of chronic respiratory disease, such as Bronchial Asthma and Chronic Obstructive Pulmonary Disease (COPD). 4.2 DOSAGE AND METHOD OF ADMINISTRATION _ADULTS: _ 1 tablet (400 mg) 2 times daily. The dosage may be increased to 1 tablet 3 times daily according to the prescribing physician. The dosage (800 mg/day) may be decreased according to medical prescription in the very elderly patients with concomitant cardiovascular, hepatic, renal and gastric diseases, to ½ tablet 2 times daily. 4.3 CONTRAINDICATIONS This product is contraindicated in individuals who have shown hypersensitivity to its components. It is also contraindicated in lactating women. 4.4 SPECIAL WARNINGS AND SPECIAL PRECAUTIONS FOR USE The half-life of xanthine derivatives is influenced by a number of known variables. It may be prolonged in patients with severe hepatic insufficiency, in patients with end stage congestive heart failure, in those affected with chronic obstructive lung disease or concomitant infections, and in those patients taking certain other drugs (erythromycin, troleandomycin, lincomycin and other antibiotics of the same group, allopurinol, cimetidine, propanolol, and anti-flu vaccine). In these cases, a lower dose of Doxofylline may be needed. Phenytoin, other anticonvulsants and smoking may cause an increase in clearance with a shorter mean half-life: in these cases higher doses of Doxofylline may be needed. Laboratory monitoring of plasma concentration of Doxofylline is recommended in all the above situations. Use with caution in patients with hypertension, heart disease, hypoxemia, hyperthyroidism, chronic right ventricular failure, congestive heart failure, liver disease, ren קרא את המסמך השלם